Capuano B - Search Results

1

The synthesis and biological evaluation of multifunctionalised derivatives of noscapine as cytotoxic agents.

Debono AJ, Mistry SJ, Xie J, Muthiah D, Phillips J, Ventura S, Callaghan R, Pouton CW, Capuano B, Scammells PJ. Debono AJ, et al. Among authors: capuano b. ChemMedChem. 2014 Feb;9(2):399-410. doi: 10.1002/cmdc.201300395. Epub 2013 Dec 11. ChemMedChem. 2014. PMID: 24339417

2

Design strategies for bivalent ligands targeting GPCRs.

Shonberg J, Scammells PJ, Capuano B. Shonberg J, et al. Among authors: capuano b. ChemMedChem. 2011 Jun 6;6(6):963-74. doi: 10.1002/cmdc.201100101. Epub 2011 Apr 21. ChemMedChem. 2011. PMID: 21520422 Review.

3

The design, synthesis and biological evaluation of novel URB602 analogues as potential monoacylglycerol lipase inhibitors.

Szabo M, Agostino M, Malone DT, Yuriev E, Capuano B. Szabo M, et al. Among authors: capuano b. Bioorg Med Chem Lett. 2011 Nov 15;21(22):6782-7. doi: 10.1016/j.bmcl.2011.09.038. Epub 2011 Sep 18. Bioorg Med Chem Lett. 2011. PMID: 21982493

4

Synthesis and biological evaluation of N-substituted noscapine analogues.

DeBono AJ, Xie JH, Ventura S, Pouton CW, Capuano B, Scammells PJ. DeBono AJ, et al. Among authors: capuano b. ChemMedChem. 2012 Dec;7(12):2122-33. doi: 10.1002/cmdc.201200365. Epub 2012 Oct 10. ChemMedChem. 2012. PMID: 23055449

5

Novel adenosine A(2A) receptor ligands: a synthetic, functional and computational investigation of selected literature adenosine A(2A) receptor antagonists for extending into extracellular space.

Jörg M, Shonberg J, Mak FS, Miller ND, Yuriev E, Scammells PJ, Capuano B. Jörg M, et al. Among authors: capuano b. Bioorg Med Chem Lett. 2013 Jun 1;23(11):3427-33. doi: 10.1016/j.bmcl.2013.03.070. Epub 2013 Apr 2. Bioorg Med Chem Lett. 2013. PMID: 23602401

6

Synthesis and pharmacological profiling of analogues of benzyl quinolone carboxylic acid (BQCA) as allosteric modulators of the M1 muscarinic receptor.

Mistry SN, Valant C, Sexton PM, Capuano B, Christopoulos A, Scammells PJ. Mistry SN, et al. Among authors: capuano b. J Med Chem. 2013 Jun 27;56(12):5151-72. doi: 10.1021/jm400540b. Epub 2013 Jun 17. J Med Chem. 2013. PMID: 23718562

7

A structure-activity analysis of biased agonism at the dopamine D2 receptor.

Shonberg J, Herenbrink CK, López L, Christopoulos A, Scammells PJ, Capuano B, Lane JR. Shonberg J, et al. Among authors: capuano b. J Med Chem. 2013 Nov 27;56(22):9199-221. doi: 10.1021/jm401318w. Epub 2013 Nov 8. J Med Chem. 2013. PMID: 24138311

8

The dopamine D2 and adenosine A2A receptors: past, present and future trends for the treatment of Parkinson's disease.

Jorg M, Scammells PJ, Capuano B. Jorg M, et al. Among authors: capuano b. Curr Med Chem. 2014;21(27):3188-210. doi: 10.2174/1389200215666140217110716. Curr Med Chem. 2014. PMID: 24533801 Review.

9

Biased agonism at G protein-coupled receptors: the promise and the challenges--a medicinal chemistry perspective.

Shonberg J, Lopez L, Scammells PJ, Christopoulos A, Capuano B, Lane JR. Shonberg J, et al. Among authors: capuano b. Med Res Rev. 2014 Nov;34(6):1286-330. doi: 10.1002/med.21318. Epub 2014 May 5. Med Res Rev. 2014. PMID: 24796277 Review.

10

Synthesis and pharmacological evaluation of analogues of benzyl quinolone carboxylic acid (BQCA) designed to bind irreversibly to an allosteric site of the M ₁ muscarinic acetylcholine receptor.

Davie BJ, Valant C, White JM, Sexton PM, Capuano B, Christopoulos A, Scammells PJ. Davie BJ, et al. Among authors: capuano b. J Med Chem. 2014 Jun 26;57(12):5405-18. doi: 10.1021/jm500556a. Epub 2014 Jun 5. J Med Chem. 2014. PMID: 24856614

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