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Page 1
The Discovery of Novel 10,11-Dihydro-5H-dibenz[b,f]azepine SIRT2 Inhibitors.
Di Fruscia P, Ho KK, Laohasinnarong S, Khongkow M, Kroll SH, Islam SA, Sternberg MJ, Schmidtkunz K, Jung M, Lam EW, Fuchter MJ. Di Fruscia P, et al. Among authors: laohasinnarong s. Medchemcomm. 2012 Mar 1;(3):10.1039/C2MD00290F. doi: 10.1039/C2MD00290F. Medchemcomm. 2012. PMID: 24340169 Free PMC article.
The discovery of a highly selective 5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one SIRT2 inhibitor that is neuroprotective in an in vitro Parkinson's disease model.
Di Fruscia P, Zacharioudakis E, Liu C, Moniot S, Laohasinnarong S, Khongkow M, Harrison IF, Koltsida K, Reynolds CR, Schmidtkunz K, Jung M, Chapman KL, Steegborn C, Dexter DT, Sternberg MJ, Lam EW, Fuchter MJ. Di Fruscia P, et al. Among authors: laohasinnarong s. ChemMedChem. 2015 Jan;10(1):69-82. doi: 10.1002/cmdc.201402431. Epub 2014 Nov 13. ChemMedChem. 2015. PMID: 25395356
Sirtuin1 (SIRT1) in the Acetylation of Downstream Target Proteins.
Gomes AR, Yong JS, Kiew KC, Aydin E, Khongkow M, Laohasinnarong S, Lam EW. Gomes AR, et al. Among authors: laohasinnarong s. Methods Mol Biol. 2016;1436:169-88. doi: 10.1007/978-1-4939-3667-0_12. Methods Mol Biol. 2016. PMID: 27246215 Free article.
SIRT6 modulates paclitaxel and epirubicin resistance and survival in breast cancer.
Khongkow M, Olmos Y, Gong C, Gomes AR, Monteiro LJ, Yagüe E, Cavaco TB, Khongkow P, Man EP, Laohasinnarong S, Koo CY, Harada-Shoji N, Tsang JW, Coombes RC, Schwer B, Khoo US, Lam EW. Khongkow M, et al. Among authors: laohasinnarong s. Carcinogenesis. 2013 Jul;34(7):1476-86. doi: 10.1093/carcin/bgt098. Epub 2013 Mar 20. Carcinogenesis. 2013. PMID: 23514751