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The discovery of 4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)-pyrazolo-[1 ,5-a]-pyrimidine: a corticotropin-releasing factor (hCRF1) antagonist.
Gilligan PJ, Baldauf C, Cocuzza A, Chidester D, Zaczek R, Fitzgerald LW, McElroy J, Smith MA, Shen HS, Saye JA, Christ D, Trainor G, Robertson DW, Hartig P. Gilligan PJ, et al. Among authors: baldauf c. Bioorg Med Chem. 2000 Jan;8(1):181-9. doi: 10.1016/s0968-0896(99)00271-0. Bioorg Med Chem. 2000. PMID: 10968277
Crystal Structure and NMR of an α,δ-Peptide Foldamer Helix Shows Side-Chains are Well Placed for Bifunctional Catalysis: Application as a Minimalist Aldolase Mimic.
Lin Q, Lan H, Ma C, Stendall RT, Shankland K, Musgrave RA, Horton PN, Baldauf C, Hofmann HJ, Butts CP, Müller MM, Cobb AJA. Lin Q, et al. Among authors: baldauf c. Angew Chem Int Ed Engl. 2023 Sep 4;62(36):e202305326. doi: 10.1002/anie.202305326. Epub 2023 Jun 14. Angew Chem Int Ed Engl. 2023. PMID: 37218617 Free PMC article.
A beta/gamma motif to mimic alpha-helical turns in proteins.
Rezaei Araghi R, Jäckel C, Cölfen H, Salwiczek M, Völkel A, Wagner SC, Wieczorek S, Baldauf C, Koksch B. Rezaei Araghi R, et al. Among authors: baldauf c. Chembiochem. 2010 Feb 15;11(3):335-9. doi: 10.1002/cbic.200900700. Chembiochem. 2010. PMID: 20039254 No abstract available.
How cations change peptide structure.
Baldauf C, Pagel K, Warnke S, von Helden G, Koksch B, Blum V, Scheffler M. Baldauf C, et al. Chemistry. 2013 Aug 19;19(34):11224-34. doi: 10.1002/chem.201204554. Epub 2013 Jul 12. Chemistry. 2013. PMID: 23853047
Native like helices in a specially designed β peptide in the gas phase.
Schubert F, Pagel K, Rossi M, Warnke S, Salwiczek M, Koksch B, von Helden G, Blum V, Baldauf C, Scheffler M. Schubert F, et al. Among authors: baldauf c. Phys Chem Chem Phys. 2015 Feb 21;17(7):5376-85. doi: 10.1039/c4cp05216a. Phys Chem Chem Phys. 2015. PMID: 25611682
113 results