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Application of SNP microarrays to the genome-wide analysis of chromosomal instability in premalignant airway lesions.
Nakachi I, Rice JL, Coldren CD, Edwards MG, Stearman RS, Glidewell SC, Varella-Garcia M, Franklin WA, Keith RL, Lewis MT, Gao B, Merrick DT, Miller YE, Geraci MW. Nakachi I, et al. Among authors: lewis mt. Cancer Prev Res (Phila). 2014 Feb;7(2):255-65. doi: 10.1158/1940-6207.CAPR-12-0485. Epub 2013 Dec 17. Cancer Prev Res (Phila). 2014. PMID: 24346345 Free PMC article.
Endobronchial miRNAs as biomarkers in lung cancer chemoprevention.
Mascaux C, Feser WJ, Lewis MT, Barón AE, Coldren CD, Merrick DT, Kennedy TC, Eckelberger JI, Rozeboom LM, Franklin WA, Minna JD, Bunn PA, Miller YE, Keith RL, Hirsch FR. Mascaux C, et al. Among authors: lewis mt. Cancer Prev Res (Phila). 2013 Feb;6(2):100-8. doi: 10.1158/1940-6207.CAPR-12-0382. Epub 2012 Dec 26. Cancer Prev Res (Phila). 2013. PMID: 23268837 Free PMC article. Clinical Trial.
Chromosomal aneusomy in bronchial high-grade lesions is associated with invasive lung cancer.
Jonsson S, Varella-Garcia M, Miller YE, Wolf HJ, Byers T, Braudrick S, Kiatsimkul P, Lewis M, Kennedy TC, Keith RL, Bjornsson J, McWilliams A, Lam S, Hirsch FR, Franklin WA. Jonsson S, et al. Am J Respir Crit Care Med. 2008 Feb 1;177(3):342-7. doi: 10.1164/rccm.200708-1142OC. Epub 2007 Nov 7. Am J Respir Crit Care Med. 2008. PMID: 17989344 Free PMC article.
A randomized phase II chemoprevention trial of 13-CIS retinoic acid with or without alpha tocopherol or observation in subjects at high risk for lung cancer.
Kelly K, Kittelson J, Franklin WA, Kennedy TC, Klein CE, Keith RL, Dempsey EC, Lewis M, Jackson MK, Hirsch FR, Bunn PA, Miller YE. Kelly K, et al. Cancer Prev Res (Phila). 2009 May;2(5):440-9. doi: 10.1158/1940-6207.CAPR-08-0136. Epub 2009 Apr 28. Cancer Prev Res (Phila). 2009. PMID: 19401528 Free PMC article. Clinical Trial.
Bronchial epithelial Ki-67 index is related to histology, smoking, and gender, but not lung cancer or chronic obstructive pulmonary disease.
Miller YE, Blatchford P, Hyun DS, Keith RL, Kennedy TC, Wolf H, Byers T, Bunn PA Jr, Lewis MT, Franklin WA, Hirsch FR, Kittelson J. Miller YE, et al. Among authors: lewis mt. Cancer Epidemiol Biomarkers Prev. 2007 Nov;16(11):2425-31. doi: 10.1158/1055-9965.EPI-07-0220. Cancer Epidemiol Biomarkers Prev. 2007. PMID: 18006932
A precision oncology-focused deep learning framework for personalized selection of cancer therapy.
Sederman C, Yang CH, Cortes-Sanchez E, Di Sera T, Huang X, Scherer SD, Zhao L, Chu Z, White ER, Atkinson A, Wagstaff J, Varley KE, Lewis MT, Qiao Y, Welm BE, Welm AL, Marth GT. Sederman C, et al. Among authors: lewis mt. bioRxiv [Preprint]. 2024 Dec 16:2024.12.12.628190. doi: 10.1101/2024.12.12.628190. bioRxiv. 2024. PMID: 39763776 Free PMC article. Preprint.
Patient-Derived Xenografts of Triple-Negative Breast Cancer Enable Deconvolution and Prediction of Chemotherapy Responses.
Lei JT, Dobrolecki LE, Huang C, Srinivasan RR, Vasaikar SV, Lewis AN, Sallas C, Zhao N, Cao J, Landua JD, Moon CI, Liao Y, Hilsenbeck SG, Osborne CK, Rimawi MF, Ellis MJ, Petrosyan V, Wen B, Li K, Saltzman AB, Jain A, Malovannaya A, Wulf GM, Marangoni E, Li S, Kraushaar DC, Wang T, Damodaran S, Zheng X, Meric-Bernstam F, Echeverria GV, Anurag M, Chen X, Welm BE, Welm AL, Zhang B, Lewis MT. Lei JT, et al. Among authors: lewis mt. bioRxiv [Preprint]. 2025 Jan 8:2024.12.09.627518. doi: 10.1101/2024.12.09.627518. bioRxiv. 2025. PMID: 39713418 Free PMC article. Preprint.
UBA1 inhibition sensitizes cancer cells to PARP inhibitors.
Awasthi S, Dobrolecki LE, Sallas C, Zhang X, Li Y, Khazaei S, Ghosh S, Jeter CR, Liu J, Mills GB, Westin SN, Lewis MT, Peng W, Sood AK, Yap TA, Yi SS, McGrail DJ, Sahni N. Awasthi S, et al. Among authors: lewis mt. Cell Rep Med. 2024 Dec 17;5(12):101834. doi: 10.1016/j.xcrm.2024.101834. Epub 2024 Dec 2. Cell Rep Med. 2024. PMID: 39626673 Free PMC article.
IRE1α silences dsRNA to prevent taxane-induced pyroptosis in triple-negative breast cancer.
Xu L, Peng F, Luo Q, Ding Y, Yuan F, Zheng L, He W, Zhang SS, Fu X, Liu J, Mutlu AS, Wang S, Nehring RB, Li X, Tang Q, Li C, Lv X, Dobrolecki LE, Zhang W, Han D, Zhao N, Jaehnig E, Wang J, Wu W, Graham DA, Li Y, Chen R, Peng W, Chen Y, Catic A, Zhang Z, Zhang B, Mustoe AM, Koong AC, Miles G, Lewis MT, Wang MC, Rosenberg SM, O'Malley BW, Westbrook TF, Xu H, Zhang XH, Osborne CK, Li JB, Ellis MJ, Rimawi MF, Rosen JM, Chen X. Xu L, et al. Among authors: lewis mt. Cell. 2024 Dec 12;187(25):7248-7266.e34. doi: 10.1016/j.cell.2024.09.032. Epub 2024 Oct 16. Cell. 2024. PMID: 39419025
Three-dimensional analysis of mitochondria in a patient-derived xenograft model of triple negative breast cancer reveals mitochondrial network remodeling following chemotherapy treatments.
Berner MJ, Beasley HK, Vue Z, Lane A, Vang L, Baek ML, Marshall AG, Killion M, Zeleke F, Shao B, Parker D, Peterson A, Rhoades JS, Scudese E, Dobrolecki LE, Lewis MT, Hinton A Jr, Echeverria GV. Berner MJ, et al. Among authors: lewis mt. bioRxiv [Preprint]. 2024 Sep 9:2024.09.09.611245. doi: 10.1101/2024.09.09.611245. bioRxiv. 2024. PMID: 39314272 Free PMC article. Preprint.
188 results