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218 results

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A T cell receptor specific for an HLA-A*03:01-restricted epitope in the endogenous retrovirus ERV-K-Env exhibits limited recognition of its cognate epitope.
Grundy EE, Shaw LC, Wang L, Lee AV, Argueta JC, Powell DJ Jr, Ostrowski M, Jones RB, Cruz CRY, Gordish-Dressman H, Chappell NP, Bollard CM, Chiappinelli KB. Grundy EE, et al. Among authors: powell dj jr. Mob DNA. 2024 Oct 9;15(1):19. doi: 10.1186/s13100-024-00333-w. Mob DNA. 2024. PMID: 39385229 Free PMC article.
Natural TCRs targeting KRASG12V display fine specificity and sensitivity to human solid tumors.
Bear AS, Nadler RB, O'Hara MH, Stanton KL, Xu C, Saporito RJ, Rech AJ, Baroja ML, Blanchard T, Elliott MH, Ford MJ, Jones R, Patel S, Brennan A, O'Neil Z, Powell DJ Jr, Vonderheide RH, Linette GP, Carreno BM. Bear AS, et al. Among authors: powell dj jr. J Clin Invest. 2024 Sep 17;134(21):e175790. doi: 10.1172/JCI175790. J Clin Invest. 2024. PMID: 39287991 Free PMC article. Clinical Trial.
CD5 deletion enhances the antitumor activity of adoptive T cell therapies.
Patel RP, Ghilardi G, Zhang Y, Chiang YH, Xie W, Guruprasad P, Kim KH, Chun I, Angelos MG, Pajarillo R, Hong SJ, Lee YG, Shestova O, Shaw C, Cohen I, Gupta A, Vu T, Qian D, Yang S, Nimmagadda A, Snook AE, Siciliano N, Rotolo A, Inamdar A, Harris J, Ugwuanyi O, Wang M, Carturan A, Paruzzo L, Chen L, Ballard HJ, Blanchard T, Xu C, Abdel-Mohsen M, Gabunia K, Wysocka M, Linette GP, Carreno B, Barrett DM, Teachey DT, Posey AD, Powell DJ Jr, Sauter CT, Pileri S, Pillai V, Scholler J, Rook AH, Schuster SJ, Barta SK, Porazzi P, Ruella M. Patel RP, et al. Among authors: powell dj jr. Sci Immunol. 2024 Jul 19;9(97):eadn6509. doi: 10.1126/sciimmunol.adn6509. Epub 2024 Jul 19. Sci Immunol. 2024. PMID: 39028827
Limited Immunogenicity of an HLA-A*03:01-restricted Epitope of Erv-k-env in Non-hiv-1 Settings: Implications for Adoptive Cell Therapy in Cancer.
Grundy EE, Shaw LC, Wang L, Powell DJ, Ostrowski M, Jones RB, Cruz CRY, Gordish-Dressman H, Bollard CM, Chiappinelli KB. Grundy EE, et al. Among authors: powell dj. Res Sq [Preprint]. 2024 May 30:rs.3.rs-4432372. doi: 10.21203/rs.3.rs-4432372/v1. Res Sq. 2024. Update in: Mob DNA. 2024 Oct 9;15(1):19. doi: 10.1186/s13100-024-00333-w PMID: 38854052 Free PMC article. Updated. Preprint.
Adoptive T cell therapy for ovarian cancer.
Gitto SB, Ihewulezi CJN, Powell DJ Jr. Gitto SB, et al. Among authors: powell dj jr. Gynecol Oncol. 2024 Jul;186:77-84. doi: 10.1016/j.ygyno.2024.04.001. Epub 2024 Apr 10. Gynecol Oncol. 2024. PMID: 38603955 Review.
CD137+ tumor infiltrating lymphocytes predicts ovarian cancer survival.
Tubridy EA, Eiva MA, Liu F, Omran DK, Gysler S, Brown EG, Roy AG, Zeng Y, Oh J, Cao Q, Gitto SB, Powell DJ Jr. Tubridy EA, et al. Among authors: powell dj jr. Gynecol Oncol. 2024 May;184:74-82. doi: 10.1016/j.ygyno.2024.01.029. Epub 2024 Jan 29. Gynecol Oncol. 2024. PMID: 38290413
218 results