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MED15, encoding a subunit of the mediator complex, is overexpressed at high frequency in castration-resistant prostate cancer.
Adler D, Menon R, Braun M, Offermann A, Queisser A, Boehm D, Vogel W, Rüenauver K, Ruiz C, Zellweger T, Svensson M, Andren O, Kristiansen G, Wernert N, Bubendorf L, Kirfel J, Biskup S, Perner S. Adler D, et al. Among authors: kirfel j. Int J Cancer. 2014 Jul 1;135(1):19-26. doi: 10.1002/ijc.28647. Epub 2013 Dec 9. Int J Cancer. 2014. PMID: 24374838
Fibroblast growth factor receptor 1 amplification is a common event in squamous cell carcinoma of the head and neck.
Göke F, Bode M, Franzen A, Kirsten R, Goltz D, Göke A, Sharma R, Boehm D, Vogel W, Wagner P, Lengerke C, Kristiansen G, Kirfel J, Van Bremen T, Bootz F, Heasley LE, Schröck A, Perner S. Göke F, et al. Among authors: kirfel j. Mod Pathol. 2013 Oct;26(10):1298-306. doi: 10.1038/modpathol.2013.58. Epub 2013 Apr 26. Mod Pathol. 2013. PMID: 23619603 Free article.
Increased circulating levels of neurotrophins and elevated expression of their high-affinity receptors on skin and gut mast cells in mastocytosis.
Peng WM, Maintz L, Allam JP, Raap U, Gütgemann I, Kirfel J, Wardelmann E, Perner S, Zhao W, Fimmers R, Walgenbach K, Oldenburg J, Schwartz LB, Novak N. Peng WM, et al. Among authors: kirfel j. Blood. 2013 Sep 5;122(10):1779-88. doi: 10.1182/blood-2012-12-469882. Epub 2013 Jul 18. Blood. 2013. PMID: 23869086 Free article.
MED12 overexpression is a frequent event in castration-resistant prostate cancer.
Adler D, Offermann A, Braun M, Menon R, Syring I, Nowak M, Halbach R, Vogel W, Ruiz C, Zellweger T, Rentsch CA, Svensson M, Andren O, Bubendorf L, Biskup S, Duensing S, Kirfel J, Perner S. Adler D, et al. Among authors: kirfel j. Endocr Relat Cancer. 2014 Aug;21(4):663-675. doi: 10.1530/ERC-14-0171. Epub 2014 Jun 17. Endocr Relat Cancer. 2014. PMID: 24938407
SRC inhibition represents a potential therapeutic strategy in liposarcoma.
Sievers E, Trautmann M, Kindler D, Huss S, Gruenewald I, Dirksen U, Renner M, Mechtersheimer G, Pedeutour F, Åman P, Nishio J, Schildhaus HU, Kirfel J, Schirmacher P, Wardelmann E, Buettner R, Hartmann W. Sievers E, et al. Among authors: kirfel j. Int J Cancer. 2015 Dec 1;137(11):2578-88. doi: 10.1002/ijc.29645. Epub 2015 Jul 6. Int J Cancer. 2015. PMID: 26084847
Low-level APC mutational mosaicism is the underlying cause in a substantial fraction of unexplained colorectal adenomatous polyposis cases.
Spier I, Drichel D, Kerick M, Kirfel J, Horpaopan S, Laner A, Holzapfel S, Peters S, Adam R, Zhao B, Becker T, Lifton RP, Perner S, Hoffmann P, Kristiansen G, Timmermann B, Nöthen MM, Holinski-Feder E, Schweiger MR, Aretz S. Spier I, et al. Among authors: kirfel j. J Med Genet. 2016 Mar;53(3):172-9. doi: 10.1136/jmedgenet-2015-103468. Epub 2015 Nov 27. J Med Genet. 2016. PMID: 26613750
112 results