Forbes N - Search Results

1

Identification of adaptive mutations in the influenza A virus non-structural 1 gene that increase cytoplasmic localization and differentially regulate host gene expression.

Forbes N, Selman M, Pelchat M, Jia JJ, Stintzi A, Brown EG. Forbes N, et al. PLoS One. 2013 Dec 31;8(12):e84673. doi: 10.1371/journal.pone.0084673. eCollection 2013. PLoS One. 2013. PMID: 24391972 Free PMC article.

2

Improved and simplified recombineering approach for influenza virus reverse genetics.

Liu Q, Wang S, Ma G, Pu J, Forbes NE, Brown EG, Liu JH. Liu Q, et al. J Mol Genet Med. 2009 Dec 1;3(2):225-31. doi: 10.4172/1747-0862.1000039. J Mol Genet Med. 2009. PMID: 20076795 Free PMC article.

3

PB2 and hemagglutinin mutations are major determinants of host range and virulence in mouse-adapted influenza A virus.

Ping J, Dankar SK, Forbes NE, Keleta L, Zhou Y, Tyler S, Brown EG. Ping J, et al. J Virol. 2010 Oct;84(20):10606-18. doi: 10.1128/JVI.01187-10. Epub 2010 Aug 11. J Virol. 2010. PMID: 20702632 Free PMC article.

4

Influenza A virus NS1 gene mutations F103L and M106I increase replication and virulence.

Dankar SK, Wang S, Ping J, Forbes NE, Keleta L, Li Y, Brown EG. Dankar SK, et al. Virol J. 2011 Jan 12;8:13. doi: 10.1186/1743-422X-8-13. Virol J. 2011. PMID: 21226922 Free PMC article.

5

Genomic and protein structural maps of adaptive evolution of human influenza A virus to increased virulence in the mouse.

Ping J, Keleta L, Forbes NE, Dankar S, Stecho W, Tyler S, Zhou Y, Babiuk L, Weingartl H, Halpin RA, Boyne A, Bera J, Hostetler J, Fedorova NB, Proudfoot K, Katzel DA, Stockwell TB, Ghedin E, Spiro DJ, Brown EG. Ping J, et al. PLoS One. 2011;6(6):e21740. doi: 10.1371/journal.pone.0021740. Epub 2011 Jun 30. PLoS One. 2011. PMID: 21738783 Free PMC article.

6

Multifunctional adaptive NS1 mutations are selected upon human influenza virus evolution in the mouse.

Forbes NE, Ping J, Dankar SK, Jia JJ, Selman M, Keleta L, Zhou Y, Brown EG. Forbes NE, et al. PLoS One. 2012;7(2):e31839. doi: 10.1371/journal.pone.0031839. Epub 2012 Feb 21. PLoS One. 2012. PMID: 22363747 Free PMC article.

7

Low-pathogenic avian influenza virus A/turkey/Ontario/6213/1966 (H5N1) is the progenitor of highly pathogenic A/turkey/Ontario/7732/1966 (H5N9).

Ping J, Selman M, Tyler S, Forbes N, Keleta L, Brown EG. Ping J, et al. Among authors: forbes n. J Gen Virol. 2012 Aug;93(Pt 8):1649-1657. doi: 10.1099/vir.0.042895-0. Epub 2012 May 16. J Gen Virol. 2012. PMID: 22592261 Free PMC article.

8

Generation and characterization of a new panel of broadly reactive anti-NS1 mAbs for detection of influenza A virus.

Rahim MN, Selman M, Sauder PJ, Forbes NE, Stecho W, Xu W, Lebar M, Brown EG, Coombs KM. Rahim MN, et al. J Gen Virol. 2013 Mar;94(Pt 3):593-605. doi: 10.1099/vir.0.046649-0. Epub 2012 Dec 5. J Gen Virol. 2013. PMID: 23223621

9

The universal epitope of influenza A viral neuraminidase fundamentally contributes to enzyme activity and viral replication.

Doyle TM, Jaentschke B, Van Domselaar G, Hashem AM, Farnsworth A, Forbes NE, Li C, Wang J, He R, Brown EG, Li X. Doyle TM, et al. J Biol Chem. 2013 Jun 21;288(25):18283-9. doi: 10.1074/jbc.M113.468884. Epub 2013 May 3. J Biol Chem. 2013. PMID: 23645684 Free PMC article.

10

Influenza A/Hong Kong/156/1997(H5N1) virus NS1 gene mutations F103L and M106I both increase IFN antagonism, virulence and cytoplasmic localization but differ in binding to RIG-I and CPSF30.

Dankar SK, Miranda E, Forbes NE, Pelchat M, Tavassoli A, Selman M, Ping J, Jia J, Brown EG. Dankar SK, et al. Virol J. 2013 Jul 25;10:243. doi: 10.1186/1743-422X-10-243. Virol J. 2013. PMID: 23886034 Free PMC article.

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