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Page 1
Loss of LRPPRC causes ATP synthase deficiency.
Mourier A, Ruzzenente B, Brandt T, Kühlbrandt W, Larsson NG. Mourier A, et al. Among authors: larsson ng. Hum Mol Genet. 2014 May 15;23(10):2580-92. doi: 10.1093/hmg/ddt652. Epub 2014 Jan 6. Hum Mol Genet. 2014. PMID: 24399447 Free PMC article.
LRPPRC is a mitochondrial matrix protein that is conserved in metazoans.
Sterky FH, Ruzzenente B, Gustafsson CM, Samuelsson T, Larsson NG. Sterky FH, et al. Among authors: larsson ng. Biochem Biophys Res Commun. 2010 Aug 6;398(4):759-64. doi: 10.1016/j.bbrc.2010.07.019. Epub 2010 Jul 13. Biochem Biophys Res Commun. 2010. PMID: 20633537
MTERF4 regulates translation by targeting the methyltransferase NSUN4 to the mammalian mitochondrial ribosome.
Cámara Y, Asin-Cayuela J, Park CB, Metodiev MD, Shi Y, Ruzzenente B, Kukat C, Habermann B, Wibom R, Hultenby K, Franz T, Erdjument-Bromage H, Tempst P, Hallberg BM, Gustafsson CM, Larsson NG. Cámara Y, et al. Among authors: larsson ng. Cell Metab. 2011 May 4;13(5):527-39. doi: 10.1016/j.cmet.2011.04.002. Cell Metab. 2011. PMID: 21531335 Free article.
LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAs.
Ruzzenente B, Metodiev MD, Wredenberg A, Bratic A, Park CB, Cámara Y, Milenkovic D, Zickermann V, Wibom R, Hultenby K, Erdjument-Bromage H, Tempst P, Brandt U, Stewart JB, Gustafsson CM, Larsson NG. Ruzzenente B, et al. Among authors: larsson ng. EMBO J. 2012 Jan 18;31(2):443-56. doi: 10.1038/emboj.2011.392. Epub 2011 Nov 1. EMBO J. 2012. PMID: 22045337 Free PMC article.
205 results