Dosa PI - Search Results

1

From HTS to Phase I: the Institute for Therapeutics Discovery and Development at the University of Minnesota.

Dosa PI, Georg GI, Gurvich VJ, Hawkinson JE, Walters MA, Wong HL. Dosa PI, et al. Comb Chem High Throughput Screen. 2014 Mar;17(3):231-40. doi: 10.2174/1386207317666140109122033. Comb Chem High Throughput Screen. 2014. PMID: 24409956

2

Synthesis of novel analogs of cabergoline: improving cardiovascular safety by removing 5-HT2B receptor agonism.

Dosa PI, Ward T, Walters MA, Kim SW. Dosa PI, et al. ACS Med Chem Lett. 2013 Feb 14;4(2):254-258. doi: 10.1021/ml3003814. ACS Med Chem Lett. 2013. PMID: 23606928 Free PMC article.

3

7-Methylation of Chenodeoxycholic Acid Derivatives Yields a Substantial Increase in TGR5 Receptor Potency.

Nakhi A, McDermott CM, Stoltz KL, John K, Hawkinson JE, Ambrose EA, Khoruts A, Sadowsky MJ, Dosa PI. Nakhi A, et al. Among authors: dosa pi. J Med Chem. 2019 Jul 25;62(14):6824-6830. doi: 10.1021/acs.jmedchem.9b00770. Epub 2019 Jul 3. J Med Chem. 2019. PMID: 31268316

4

Structural modifications that increase gut restriction of bile acid derivatives.

Nakhi A, Wong HL, Weldy M, Khoruts A, Sadowsky MJ, Dosa PI. Nakhi A, et al. Among authors: dosa pi. RSC Med Chem. 2021 Feb 12;12(3):394-405. doi: 10.1039/d0md00425a. eCollection 2021 Mar 1. RSC Med Chem. 2021. PMID: 34046622 Free PMC article.

5

Algorithm-driven optimization of cryopreservation protocols for transfusion model cell types including Jurkat cells and mesenchymal stem cells.

Pollock K, Budenske JW, McKenna DH, Dosa PI, Hubel A. Pollock K, et al. Among authors: dosa pi. J Tissue Eng Regen Med. 2017 Oct;11(10):2806-2815. doi: 10.1002/term.2175. Epub 2016 May 27. J Tissue Eng Regen Med. 2017. PMID: 27229375 Free PMC article.

6

Analogs of the ATP-Sensitive Potassium (KATP) Channel Opener Cromakalim with in Vivo Ocular Hypotensive Activity.

Roy Chowdhury U, Viker KB, Stoltz KL, Holman BH, Fautsch MP, Dosa PI. Roy Chowdhury U, et al. Among authors: dosa pi. J Med Chem. 2016 Jul 14;59(13):6221-31. doi: 10.1021/acs.jmedchem.6b00406. Epub 2016 Jul 1. J Med Chem. 2016. PMID: 27367033 Free PMC article.

7

Tactical Approaches to Interconverting GPCR Agonists and Antagonists.

Dosa PI, Amin EA. Dosa PI, et al. J Med Chem. 2016 Feb 11;59(3):810-40. doi: 10.1021/acs.jmedchem.5b00982. Epub 2015 Sep 21. J Med Chem. 2016. PMID: 26390077 Review.

8

Ursodeoxycholic Acid Inhibits Clostridium difficile Spore Germination and Vegetative Growth, and Prevents the Recurrence of Ileal Pouchitis Associated With the Infection.

Weingarden AR, Chen C, Zhang N, Graiziger CT, Dosa PI, Steer CJ, Shaughnessy MK, Johnson JR, Sadowsky MJ, Khoruts A. Weingarden AR, et al. Among authors: dosa pi. J Clin Gastroenterol. 2016 Sep;50(8):624-30. doi: 10.1097/MCG.0000000000000427. J Clin Gastroenterol. 2016. PMID: 26485102 Free PMC article.

9

Ocular Hypotensive Effects of the ATP-Sensitive Potassium Channel Opener Cromakalim in Human and Murine Experimental Model Systems.

Roy Chowdhury U, Bahler CK, Holman BH, Dosa PI, Fautsch MP. Roy Chowdhury U, et al. Among authors: dosa pi. PLoS One. 2015 Nov 4;10(11):e0141783. doi: 10.1371/journal.pone.0141783. eCollection 2015. PLoS One. 2015. PMID: 26535899 Free PMC article.

10

Changes in Colonic Bile Acid Composition following Fecal Microbiota Transplantation Are Sufficient to Control Clostridium difficile Germination and Growth.

Weingarden AR, Dosa PI, DeWinter E, Steer CJ, Shaughnessy MK, Johnson JR, Khoruts A, Sadowsky MJ. Weingarden AR, et al. Among authors: dosa pi. PLoS One. 2016 Jan 20;11(1):e0147210. doi: 10.1371/journal.pone.0147210. eCollection 2016. PLoS One. 2016. PMID: 26789728 Free PMC article.

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