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Ultra-High-Throughput Screening of Natural Product Extracts to Identify Proapoptotic Inhibitors of Bcl-2 Family Proteins.
Hassig CA, Zeng FY, Kung P, Kiankarimi M, Kim S, Diaz PW, Zhai D, Welsh K, Morshedian S, Su Y, O'Keefe B, Newman DJ, Rusman Y, Kaur H, Salomon CE, Brown SG, Baire B, Michel AR, Hoye TR, Francis S, Georg GI, Walters MA, Divlianska DB, Roth GP, Wright AE, Reed JC. Hassig CA, et al. Among authors: walters ma. J Biomol Screen. 2014 Sep;19(8):1201-11. doi: 10.1177/1087057114536227. Epub 2014 May 27. J Biomol Screen. 2014. PMID: 24870016 Free PMC article.
Mitigating risk in academic preclinical drug discovery.
Dahlin JL, Inglese J, Walters MA. Dahlin JL, et al. Among authors: walters ma. Nat Rev Drug Discov. 2015 Apr;14(4):279-94. doi: 10.1038/nrd4578. Nat Rev Drug Discov. 2015. PMID: 25829283 Free PMC article. Review.
Reduction of protein kinase A-mediated phosphorylation of ATXN1-S776 in Purkinje cells delays onset of Ataxia in a SCA1 mouse model.
Pérez Ortiz JM, Mollema N, Toker N, Adamski CJ, O'Callaghan B, Duvick L, Friedrich J, Walters MA, Strasser J, Hawkinson JE, Zoghbi HY, Henzler C, Orr HT, Lagalwar S. Pérez Ortiz JM, et al. Among authors: walters ma. Neurobiol Dis. 2018 Aug;116:93-105. doi: 10.1016/j.nbd.2018.05.002. Epub 2018 May 11. Neurobiol Dis. 2018. PMID: 29758256 Free PMC article.
Risk Management in Early Discovery Medicinal Chemistry.
Singh G, Dahlin JL, Walters MA. Singh G, et al. Among authors: walters ma. Methods Enzymol. 2018;610:1-25. doi: 10.1016/bs.mie.2018.09.012. Epub 2018 Oct 19. Methods Enzymol. 2018. PMID: 30390795
104 results