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Page 1
Genetic variation at 11q23.1 confers colorectal cancer risk by dysregulation of colonic tuft cell transcriptional activator POU2AF2.
Rajasekaran V, Harris BT, Osborn RT, Smillie C, Donnelly K, Bacou M, Esiri-Bloom E, Ooi LY, Allan M, Walker M, Reid S, Meynert A, Grimes G, Blackmur JP, Vaughan-Shaw PG, Law PJ, Fernández-Rozadilla C, Tomlinson I, Houlston RS, Myant KB, Din FV, Timofeeva M, Dunlop MG, Farrington SM. Rajasekaran V, et al. Among authors: law pj. Gut. 2024 Nov 28:gutjnl-2024-332121. doi: 10.1136/gutjnl-2024-332121. Online ahead of print. Gut. 2024. PMID: 39609081 Free article.
DBPR116, a Prodrug of BPRMU191, in Combination with Naltrexone as a Safer Opioid Analgesic Than Morphine via Peripheral Administration.
Lin SY, Chang YC, Tien YW, Kuo YH, Chang HF, Ou LC, Chen YP, Chang KH, Hsu YT, Huang YC, Yang CM, Law PY, Xi JH, Tao PL, Loh HH, Yeh TK, Zhuang H, Hsieh HP, Shih C, Chen CT, Yeh SH, Ueng SH. Lin SY, et al. Among authors: law py. J Med Chem. 2024 Nov 14;67(21):19777-19790. doi: 10.1021/acs.jmedchem.4c02107. Epub 2024 Oct 29. J Med Chem. 2024. PMID: 39473174
Genomic landscape of adult testicular germ cell tumours in the 100,000 Genomes Project.
Ní Leathlobhair M, Frangou A, Kinnersley B, Cornish AJ, Chubb D, Lakatos E, Arumugam P, Gruber AJ, Law P, Tapinos A, Jakobsdottir GM, Peneva I, Sahli A, Smyth EM, Ball RY, Sylva R, Benes K, Stark D, Young RJ, Lee ATJ, Wolverson V, Houlston RS, Sosinsky A, Protheroe A, Murray MJ, Wedge DC, Verrill C; Testicular Cancer Genomics England Clinical Interpretation Partnership Consortium; Genomics England Research Consortium. Ní Leathlobhair M, et al. Among authors: law p. Nat Commun. 2024 Oct 26;15(1):9247. doi: 10.1038/s41467-024-53193-6. Nat Commun. 2024. PMID: 39461959 Free PMC article.
The genomic landscape of 2,023 colorectal cancers.
Cornish AJ, Gruber AJ, Kinnersley B, Chubb D, Frangou A, Caravagna G, Noyvert B, Lakatos E, Wood HM, Thorn S, Culliford R, Arnedo-Pac C, Househam J, Cross W, Sud A, Law P, Leathlobhair MN, Hawari A, Woolley C, Sherwood K, Feeley N, Gül G, Fernandez-Tajes J, Zapata L, Alexandrov LB, Murugaesu N, Sosinsky A, Mitchell J, Lopez-Bigas N, Quirke P, Church DN, Tomlinson IPM, Sottoriva A, Graham TA, Wedge DC, Houlston RS. Cornish AJ, et al. Among authors: law p. Nature. 2024 Sep;633(8028):127-136. doi: 10.1038/s41586-024-07747-9. Epub 2024 Aug 7. Nature. 2024. PMID: 39112709 Free PMC article.
Deciphering the genetics and mechanisms of predisposition to multiple myeloma.
Went M, Duran-Lozano L, Halldorsson GH, Gunnell A, Ugidos-Damboriena N, Law P, Ekdahl L, Sud A, Thorleifsson G, Thodberg M, Olafsdottir T, Lamarca-Arrizabalaga A, Cafaro C, Niroula A, Ajore R, Lopez de Lapuente Portilla A, Ali Z, Pertesi M, Goldschmidt H, Stefansdottir L, Kristinsson SY, Stacey SN, Love TJ, Rognvaldsson S, Hajek R, Vodicka P, Pettersson-Kymmer U, Späth F, Schinke C, Van Rhee F, Sulem P, Ferkingstad E, Hjorleifsson Eldjarn G, Mellqvist UH, Jonsdottir I, Morgan G, Sonneveld P, Waage A, Weinhold N, Thomsen H, Försti A, Hansson M, Juul-Vangsted A, Thorsteinsdottir U, Hemminki K, Kaiser M, Rafnar T, Stefansson K, Houlston R, Nilsson B. Went M, et al. Among authors: law p. Nat Commun. 2024 Aug 5;15(1):6644. doi: 10.1038/s41467-024-50932-7. Nat Commun. 2024. PMID: 39103364 Free PMC article.
759 results