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Synthesis and biological evaluation of novel 2-phenylquinazoline-4-amine derivatives: identification of 6-phenyl-8H-benzo[g]quinazolino[4,3-b]quinazolin-8-one as a highly potent inducer of NAD(P)H quinone oxidoreductase 1.
Ghorab MM, Alsaid MS, El-Gazzar MG, Higgins M, Dinkova-Kostova AT, Shahat AA. Ghorab MM, et al. Among authors: higgins m. J Enzyme Inhib Med Chem. 2016;31(sup1):34-39. doi: 10.3109/14756366.2016.1163343. Epub 2016 Apr 1. J Enzyme Inhib Med Chem. 2016. PMID: 27033734 Free article.
Synthesis and biological evaluation of biotin conjugates of (±)-(4bS,8aR,10aS)-10a-ethynyl-4b,8,8-trimethyl-3,7-dioxo-3,4b,7,8,8a,9,10,10a-octahydro-phenanthrene-2,6-dicarbonitrile, an activator of the Keap1/Nrf2/ARE pathway, for the isolation of its protein targets.
Saito A, Higgins M, Zheng S, Li W, Ojima I, Dinkova-Kostova AT, Honda T. Saito A, et al. Among authors: higgins m. Bioorg Med Chem Lett. 2013 Oct 15;23(20):5540-3. doi: 10.1016/j.bmcl.2013.08.058. Epub 2013 Aug 21. Bioorg Med Chem Lett. 2013. PMID: 24018193
1,656 results