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Direct interaction of garcinol and related polyisoprenylated benzophenones of Garcinia cambogia fruits with the transcription factor STAT-1 as a likely mechanism of their inhibitory effect on cytokine signaling pathways.
Masullo M, Menegazzi M, Di Micco S, Beffy P, Bifulco G, Dal Bosco M, Novelli M, Pizza C, Masiello P, Piacente S. Masullo M, et al. Among authors: menegazzi m. J Nat Prod. 2014 Mar 28;77(3):543-9. doi: 10.1021/np400804y. Epub 2014 Jan 13. J Nat Prod. 2014. PMID: 24417609
St. John's wort extract and hyperforin inhibit multiple phosphorylation steps of cytokine signaling and prevent inflammatory and apoptotic gene induction in pancreatic β cells.
Novelli M, Menegazzi M, Beffy P, Porozov S, Gregorelli A, Giacopelli D, De Tata V, Masiello P. Novelli M, et al. Among authors: menegazzi m. Int J Biochem Cell Biol. 2016 Dec;81(Pt A):92-104. doi: 10.1016/j.biocel.2016.10.017. Epub 2016 Oct 22. Int J Biochem Cell Biol. 2016. PMID: 27780755
Salviolone from Salvia miltiorrhiza Roots Impairs Cell Cycle Progression, Colony Formation, and Metalloproteinase-2 Activity in A375 Melanoma Cells: Involvement of P21(Cip1/Waf1) Expression and STAT3 Phosphorylation.
Zanrè V, Campagnari R, Cerulli A, Masullo M, Cardile A, Piacente S, Menegazzi M. Zanrè V, et al. Among authors: menegazzi m. Int J Mol Sci. 2022 Jan 20;23(3):1121. doi: 10.3390/ijms23031121. Int J Mol Sci. 2022. PMID: 35163058 Free PMC article.
104 results