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High-throughput screening platform for natural product-based drug discovery against 3 neglected tropical diseases: human African trypanosomiasis, leishmaniasis, and Chagas disease.
Annang F, Pérez-Moreno G, García-Hernández R, Cordon-Obras C, Martín J, Tormo JR, Rodríguez L, de Pedro N, Gómez-Pérez V, Valente M, Reyes F, Genilloud O, Vicente F, Castanys S, Ruiz-Pérez LM, Navarro M, Gamarro F, González-Pacanowska D. Annang F, et al. J Biomol Screen. 2015 Jan;20(1):82-91. doi: 10.1177/1087057114555846. Epub 2014 Oct 20. J Biomol Screen. 2015. PMID: 25332350
Strasseriolides display in vitro and in vivo activity against trypanosomal parasites and cause morphological and size defects in Trypanosoma cruzi.
Bosch-Navarrete C, Pérez-Moreno G, Annang F, Diaz-Gonzalez R, García-Hernández R, Rocha H, Gamarro F, Cordón-Obras C, Navarro M, Rodriguez A, Genilloud O, Reyes F, Vicente F, Ruiz-Pérez LM, González-Pacanowska D. Bosch-Navarrete C, et al. Among authors: cordon obras c. PLoS Negl Trop Dis. 2023 Sep 15;17(9):e0011592. doi: 10.1371/journal.pntd.0011592. eCollection 2023 Sep. PLoS Negl Trop Dis. 2023. PMID: 37713416 Free PMC article.
Identification and characterization of hundreds of potent and selective inhibitors of Trypanosoma brucei growth from a kinase-targeted library screening campaign.
Diaz R, Luengo-Arratta SA, Seixas JD, Amata E, Devine W, Cordon-Obras C, Rojas-Barros DI, Jimenez E, Ortega F, Crouch S, Colmenarejo G, Fiandor JM, Martin JJ, Berlanga M, Gonzalez S, Manzano P, Navarro M, Pollastri MP. Diaz R, et al. Among authors: cordon obras c. PLoS Negl Trop Dis. 2014 Oct 23;8(10):e3253. doi: 10.1371/journal.pntd.0003253. eCollection 2014 Oct. PLoS Negl Trop Dis. 2014. PMID: 25340575 Free PMC article.
15 results