Rodriguez-García A - Search Results

1

A pRb-responsive, RGD-modified, and hyaluronidase-armed canine oncolytic adenovirus for application in veterinary oncology.

Laborda E, Puig-Saus C, Rodriguez-García A, Moreno R, Cascalló M, Pastor J, Alemany R. Laborda E, et al. Mol Ther. 2014 May;22(5):986-98. doi: 10.1038/mt.2014.7. Epub 2014 Jan 22. Mol Ther. 2014. PMID: 24448161 Free PMC article.

2

Genome Editing in CAR-T Cells Using CRISPR/Cas9 Technology.

Andreu-Saumell I, Rodriguez-Garcia A, Guedan S. Andreu-Saumell I, et al. Methods Mol Biol. 2024;2748:151-165. doi: 10.1007/978-1-0716-3593-3_12. Methods Mol Biol. 2024. PMID: 38070114

3

TCRvβ-CART therapy mediates high-precision targeting of malignant T-cell clones.

Shaw LC, Poussin M, Rodriguez-Garcia A, Eggold J, Minutolo NG, Wang J, Rook AH, Schuster SJ, Powell DJ. Shaw LC, et al. Blood Adv. 2023 May 9;7(9):1885-1898. doi: 10.1182/bloodadvances.2022008798. Blood Adv. 2023. PMID: 36053778 Free PMC article.

4

The combination of i-leader truncation and gemcitabine improves oncolytic adenovirus efficacy in an immunocompetent model.

Puig-Saus C, Laborda E, Rodríguez-García A, Cascalló M, Moreno R, Alemany R. Puig-Saus C, et al. Cancer Gene Ther. 2014 Feb;21(2):68-73. doi: 10.1038/cgt.2013.85. Epub 2014 Jan 17. Cancer Gene Ther. 2014. PMID: 24434571

5

Safety and efficacy of VCN-01, an oncolytic adenovirus combining fiber HSG-binding domain replacement with RGD and hyaluronidase expression.

Rodríguez-García A, Giménez-Alejandre M, Rojas JJ, Moreno R, Bazan-Peregrino M, Cascalló M, Alemany R. Rodríguez-García A, et al. Clin Cancer Res. 2015 Mar 15;21(6):1406-18. doi: 10.1158/1078-0432.CCR-14-2213. Epub 2014 Nov 12. Clin Cancer Res. 2015. PMID: 25391696

6

Insertion of exogenous epitopes in the E3-19K of oncolytic adenoviruses to enhance TAP-independent presentation and immunogenicity.

Rodríguez-García A, Svensson E, Gil-Hoyos R, Fajardo CA, Rojas LA, Arias-Badia M, Loskog AS, Alemany R. Rodríguez-García A, et al. Gene Ther. 2015 Jul;22(7):596-601. doi: 10.1038/gt.2015.41. Epub 2015 May 21. Gene Ther. 2015. PMID: 25994521

7

VCN-01 disrupts pancreatic cancer stroma and exerts antitumor effects.

Bazan-Peregrino M, Garcia-Carbonero R, Laquente B, Álvarez R, Mato-Berciano A, Gimenez-Alejandre M, Morgado S, Rodríguez-García A, Maliandi MV, Riesco MC, Moreno R, Ginestà MM, Perez-Carreras M, Gornals JB, Prados S, Perea S, Capella G, Alemany R, Salazar R, Blasi E, Blasco C, Cascallo M, Hidalgo M. Bazan-Peregrino M, et al. J Immunother Cancer. 2021 Nov;9(11):e003254. doi: 10.1136/jitc-2021-003254. J Immunother Cancer. 2021. PMID: 35149591 Free PMC article. Clinical Trial.

8

CAR T Cells Targeting MISIIR for the Treatment of Ovarian Cancer and Other Gynecologic Malignancies.

Rodriguez-Garcia A, Sharma P, Poussin M, Boesteanu AC, Minutolo NG, Gitto SB, Omran DK, Robinson MK, Adams GP, Simpkins F, Powell DJ Jr. Rodriguez-Garcia A, et al. Mol Ther. 2020 Feb 5;28(2):548-560. doi: 10.1016/j.ymthe.2019.11.028. Epub 2019 Dec 6. Mol Ther. 2020. PMID: 31870622 Free PMC article.

9

ARI0003: Co-transduced CD19/BCMA dual-targeting CAR-T cells for the treatment of non-Hodgkin lymphoma.

Bachiller M, Barceló-Genestar N, Rodriguez-Garcia A, Alserawan L, Dobaño-López C, Giménez-Alejandre M, Castellsagué J, Colell S, Otero-Mateo M, Antoñana-Vildosola A, Español-Rego M, Ferruz N, Pascal M, Martín-Antonio B, Anguela XM, Fillat C, Olesti E, Calvo G, Juan M, Delgado J, Pérez-Galán P, Urbano-Ispizua Á, Guedan S. Bachiller M, et al. Among authors: rodriguez garcia a. Mol Ther. 2025 Jan 8;33(1):317-335. doi: 10.1016/j.ymthe.2024.11.028. Epub 2024 Nov 19. Mol Ther. 2025. PMID: 39563035 Free article.

10

CAR affinity modulates the sensitivity of CAR-T cells to PD-1/PD-L1-mediated inhibition.

Andreu-Saumell I, Rodriguez-Garcia A, Mühlgrabner V, Gimenez-Alejandre M, Marzal B, Castellsagué J, Brasó-Maristany F, Calderon H, Angelats L, Colell S, Nuding M, Soria-Castellano M, Barbao P, Prat A, Urbano-Ispizua A, Huppa JB, Guedan S. Andreu-Saumell I, et al. Nat Commun. 2024 Apr 26;15(1):3552. doi: 10.1038/s41467-024-47799-z. Nat Commun. 2024. PMID: 38670972 Free PMC article.

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