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Small molecule activators of TAK1 promotes its activity-dependent ubiquitination and TRAIL-mediated tumor cell death.
Sun W, Wu G, Tian X, Qi C, Liu J, Tong Y, Zhang M, Gao J, Cao Z, Zhang Y, Liu Z, Tian X, Wu P, Peng C, Li J, Tan L, Shan B, Liu J, Li Y, Yuan J. Sun W, et al. Among authors: liu j, liu z. Proc Natl Acad Sci U S A. 2023 Sep 26;120(39):e2308079120. doi: 10.1073/pnas.2308079120. Epub 2023 Sep 21. Proc Natl Acad Sci U S A. 2023. PMID: 37733743 Free PMC article.
Structure-based development of potent and selective type-II kinase inhibitors of RIPK1.
Qin Y, Li D, Qi C, Xiang H, Meng H, Liu J, Zhou S, Gong X, Li Y, Xu G, Zu R, Xie H, Xu Y, Xu G, Zhang Z, Chen S, Pan L, Li Y, Tan L. Qin Y, et al. Among authors: liu j. Acta Pharm Sin B. 2024 Jan;14(1):319-334. doi: 10.1016/j.apsb.2023.10.021. Epub 2023 Nov 8. Acta Pharm Sin B. 2024. PMID: 38261830 Free PMC article.
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