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Sesquiterpene dimmer (DSF-27) inhibits the release of neuroinflammatory mediators from microglia by targeting spleen tyrosine kinase (Syk) and Janus kinase 2 (Jak2): Two major non-receptor tyrosine signaling proteins involved in inflammatory events.
Zeng KW, Wang S, Dong X, Jiang Y, Jin HW, Tu PF. Zeng KW, et al. Among authors: jiang y. Toxicol Appl Pharmacol. 2014 Mar 15;275(3):244-56. doi: 10.1016/j.taap.2014.01.014. Epub 2014 Jan 28. Toxicol Appl Pharmacol. 2014. PMID: 24486434
Triterpene saponins from the leaves of Ilex kudingcha.
Tang L, Jiang Y, Chang HT, Zhao MB, Tu PF, Cui JR, Wang RQ. Tang L, et al. Among authors: jiang y. J Nat Prod. 2005 Aug;68(8):1169-74. doi: 10.1021/np050043z. J Nat Prod. 2005. PMID: 16124755
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