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Regulatory T cells require TCR signaling for their suppressive function.
Schmidt AM, Lu W, Sindhava VJ, Huang Y, Burkhardt JK, Yang E, Riese MJ, Maltzman JS, Jordan MS, Kambayashi T. Schmidt AM, et al. Among authors: riese mj. J Immunol. 2015 May 1;194(9):4362-70. doi: 10.4049/jimmunol.1402384. Epub 2015 Mar 27. J Immunol. 2015. PMID: 25821220 Free PMC article.
Diacylglycerol kinase ζ (DGKζ) and Casitas b-lineage proto-oncogene b-deficient mice have similar functional outcomes in T cells but DGKζ-deficient mice have increased T cell activation and tumor clearance.
Wesley EM, Xin G, McAllister D, Malarkannan S, Newman DK, Dwinell MB, Cui W, Johnson BD, Riese MJ. Wesley EM, et al. Among authors: riese mj. Immunohorizons. 2018 Apr 1;2(4):107-118. doi: 10.4049/immunohorizons.1700055. Immunohorizons. 2018. PMID: 30027154 Free PMC article.
49 results