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A Polymerase Theta-dependent repair pathway suppresses extensive genomic instability at endogenous G4 DNA sites.
Nat Commun. 2014;5:3216. doi: 10.1038/ncomms4216.
Nat Commun. 2014.
PMID: 24496117
Free article.
DNA damage leads to progressive replicative decline but extends the life span of long-lived mutant animals.
Lans H, Lindvall JM, Thijssen K, Karambelas AE, Cupac D, Fensgård O, Jansen G, Hoeijmakers JH, Nilsen H, Vermeulen W.
Lans H, et al. Among authors: karambelas ae.
Cell Death Differ. 2013 Dec;20(12):1709-18. doi: 10.1038/cdd.2013.126. Epub 2013 Sep 6.
Cell Death Differ. 2013.
PMID: 24013725
Free PMC article.
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Transient PLK4 overexpression accelerates tumorigenesis in p53-deficient epidermis.
Serçin Ö, Larsimont JC, Karambelas AE, Marthiens V, Moers V, Boeckx B, Le Mercier M, Lambrechts D, Basto R, Blanpain C.
Serçin Ö, et al. Among authors: karambelas ae.
Nat Cell Biol. 2016 Jan;18(1):100-10. doi: 10.1038/ncb3270. Epub 2015 Nov 23.
Nat Cell Biol. 2016.
PMID: 26595384
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BRCA1 deficiency in skin epidermis leads to selective loss of hair follicle stem cells and their progeny.
Sotiropoulou PA, Karambelas AE, Debaugnies M, Candi A, Bouwman P, Moers V, Revenco T, Rocha AS, Sekiguchi K, Jonkers J, Blanpain C.
Sotiropoulou PA, et al. Among authors: karambelas ae.
Genes Dev. 2013 Jan 1;27(1):39-51. doi: 10.1101/gad.206573.112. Epub 2012 Dec 27.
Genes Dev. 2013.
PMID: 23271346
Free PMC article.
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