Xu J - Search Results

1

DNMT3A Arg882 mutation drives chronic myelomonocytic leukemia through disturbing gene expression/DNA methylation in hematopoietic cells.

Xu J, Wang YY, Dai YJ, Zhang W, Zhang WN, Xiong SM, Gu ZH, Wang KK, Zeng R, Chen Z, Chen SJ. Xu J, et al. Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2620-5. doi: 10.1073/pnas.1400150111. Epub 2014 Feb 4. Proc Natl Acad Sci U S A. 2014. PMID: 24497509 Free PMC article.

2

Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia.

Yan XJ, Xu J, Gu ZH, Pan CM, Lu G, Shen Y, Shi JY, Zhu YM, Tang L, Zhang XW, Liang WX, Mi JQ, Song HD, Li KQ, Chen Z, Chen SJ. Yan XJ, et al. Among authors: xu j. Nat Genet. 2011 Mar 13;43(4):309-15. doi: 10.1038/ng.788. Nat Genet. 2011. PMID: 21399634

3

DNMT3A mutation leads to leukemic extramedullary infiltration mediated by TWIST1.

Xu J, Zhang W, Yan XJ, Lin XQ, Li W, Mi JQ, Li JM, Zhu J, Chen Z, Chen SJ. Xu J, et al. J Hematol Oncol. 2016 Oct 10;9(1):106. doi: 10.1186/s13045-016-0337-3. J Hematol Oncol. 2016. PMID: 27724883 Free PMC article.

4

Conditional knockin of Dnmt3a R878H initiates acute myeloid leukemia with mTOR pathway involvement.

Dai YJ, Wang YY, Huang JY, Xia L, Shi XD, Xu J, Lu J, Su XB, Yang Y, Zhang WN, Wang PP, Wu SF, Huang T, Mi JQ, Han ZG, Chen Z, Chen SJ. Dai YJ, et al. Among authors: xu j. Proc Natl Acad Sci U S A. 2017 May 16;114(20):5237-5242. doi: 10.1073/pnas.1703476114. Epub 2017 May 1. Proc Natl Acad Sci U S A. 2017. PMID: 28461508 Free PMC article.

5

DNA methyltransferases in hematologic malignancies.

Li KK, Luo LF, Shen Y, Xu J, Chen Z, Chen SJ. Li KK, et al. Among authors: xu j. Semin Hematol. 2013 Jan;50(1):48-60. doi: 10.1053/j.seminhematol.2013.01.005. Semin Hematol. 2013. PMID: 23507483 Review.

6

DNA methyltransferases and their roles in tumorigenesis.

Zhang W, Xu J. Zhang W, et al. Among authors: xu j. Biomark Res. 2017 Jan 20;5:1. doi: 10.1186/s40364-017-0081-z. eCollection 2017. Biomark Res. 2017. PMID: 28127428 Free PMC article. Review.

7

Inactivation of PBX3 and HOXA9 by down-regulating H3K79 methylation represses NPM1-mutated leukemic cell survival.

Zhang W, Zhao C, Zhao J, Zhu Y, Weng X, Chen Q, Sun H, Mi JQ, Li J, Zhu J, Chen Z, Pandolfi PP, Chen S, Yan X, Xu J. Zhang W, et al. Among authors: xu j. Theranostics. 2018 Jul 30;8(16):4359-4371. doi: 10.7150/thno.26900. eCollection 2018. Theranostics. 2018. PMID: 30214626 Free PMC article.

8

Exploratory trial of a biepitopic CAR T-targeting B cell maturation antigen in relapsed/refractory multiple myeloma.

Xu J, Chen LJ, Yang SS, Sun Y, Wu W, Liu YF, Xu J, Zhuang Y, Zhang W, Weng XQ, Wu J, Wang Y, Wang J, Yan H, Xu WB, Jiang H, Du J, Ding XY, Li B, Li JM, Fu WJ, Zhu J, Zhu L, Chen Z, Fan XF, Hou J, Li JY, Mi JQ, Chen SJ. Xu J, et al. Among authors: xu wb. Proc Natl Acad Sci U S A. 2019 May 7;116(19):9543-9551. doi: 10.1073/pnas.1819745116. Epub 2019 Apr 15. Proc Natl Acad Sci U S A. 2019. PMID: 30988175 Free PMC article. Clinical Trial.

9

CAR T-cell immunotherapy: a powerful weapon for fighting hematological B-cell malignancies.

Mi JQ, Xu J, Zhou J, Zhao W, Chen Z, Melenhorst JJ, Chen S. Mi JQ, et al. Among authors: xu j. Front Med. 2021 Dec;15(6):783-804. doi: 10.1007/s11684-021-0904-z. Epub 2021 Dec 18. Front Med. 2021. PMID: 34921673 Review.

10

TRIB3 Stabilizes High TWIST1 Expression to Promote Rapid APL Progression and ATRA Resistance.

Lin J, Zhang W, Niu LT, Zhu YM, Weng XQ, Sheng Y, Zhu J, Xu J. Lin J, et al. Among authors: xu j. Clin Cancer Res. 2019 Oct 15;25(20):6228-6242. doi: 10.1158/1078-0432.CCR-19-0510. Epub 2019 Jun 24. Clin Cancer Res. 2019. PMID: 31235507

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