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Myostatin induces degradation of sarcomeric proteins through a Smad3 signaling mechanism during skeletal muscle wasting.
Lokireddy S, McFarlane C, Ge X, Zhang H, Sze SK, Sharma M, Kambadur R. Lokireddy S, et al. Among authors: mcfarlane c. Mol Endocrinol. 2011 Nov;25(11):1936-49. doi: 10.1210/me.2011-1124. Epub 2011 Sep 29. Mol Endocrinol. 2011. Retraction in: Mol Endocrinol. 2016 Feb;30(2):274. doi: 10.1210/me.2015-1318 PMID: 21964591 Free PMC article. Retracted.
Peroxisome proliferator-activated receptor β/δ induces myogenesis by modulating myostatin activity.
Bonala S, Lokireddy S, Arigela H, Teng S, Wahli W, Sharma M, McFarlane C, Kambadur R. Bonala S, et al. Among authors: mcfarlane c. J Biol Chem. 2012 Apr 13;287(16):12935-51. doi: 10.1074/jbc.M111.319145. Epub 2012 Feb 23. J Biol Chem. 2012. Retraction in: J Biol Chem. 2016 Jul 1;291(27):14391. doi: 10.1074/jbc.A111.319145 PMID: 22362769 Free PMC article. Retracted.
Lack of Smad3 signaling leads to impaired skeletal muscle regeneration.
Ge X, Vajjala A, McFarlane C, Wahli W, Sharma M, Kambadur R. Ge X, et al. Among authors: mcfarlane c. Am J Physiol Endocrinol Metab. 2012 Jul 1;303(1):E90-102. doi: 10.1152/ajpendo.00113.2012. Epub 2012 Apr 24. Am J Physiol Endocrinol Metab. 2012. PMID: 22535746 Free article.
Myostatin induces insulin resistance via Casitas B-lineage lymphoma b (Cblb)-mediated degradation of insulin receptor substrate 1 (IRS1) protein in response to high calorie diet intake.
Bonala S, Lokireddy S, McFarlane C, Patnam S, Sharma M, Kambadur R. Bonala S, et al. Among authors: mcfarlane c. J Biol Chem. 2014 Mar 14;289(11):7654-70. doi: 10.1074/jbc.M113.529925. Epub 2014 Jan 22. J Biol Chem. 2014. Retraction in: J Biol Chem. 2016 Jul 1;291(27):14392. doi: 10.1074/jbc.A113.529925 PMID: 24451368 Free PMC article. Retracted.
186 results