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Page 1
Identification of highly efficacious glucocorticoid receptor agonists with a potential for reduced clinical bone side effects.
Harcken C, Riether D, Kuzmich D, Liu P, Betageri R, Ralph M, Emmanuel M, Reeves JT, Berry A, Souza D, Nelson RM, Kukulka A, Fadra TN, Zuvela-Jelaska L, Dinallo R, Bentzien J, Nabozny GH, Thomson DS. Harcken C, et al. Among authors: emmanuel m. J Med Chem. 2014 Feb 27;57(4):1583-98. doi: 10.1021/jm4019178. Epub 2014 Feb 7. J Med Chem. 2014. PMID: 24506830
Identification of a novel class of succinyl-nitrile-based Cathepsin S inhibitors.
Bekkali Y, Thomson DS, Betageri R, Emmanuel MJ, Hao MH, Hickey E, Liu W, Patel U, Ward YD, Young ER, Nelson R, Kukulka A, Brown ML, Crane K, White D, Freeman DM, Labadia ME, Wildeson J, Spero DM. Bekkali Y, et al. Among authors: emmanuel mj. Bioorg Med Chem Lett. 2007 May 1;17(9):2465-9. doi: 10.1016/j.bmcl.2007.02.046. Epub 2007 Feb 23. Bioorg Med Chem Lett. 2007. PMID: 17379516
Design and synthesis of dipeptide nitriles as reversible and potent Cathepsin S inhibitors.
Ward YD, Thomson DS, Frye LL, Cywin CL, Morwick T, Emmanuel MJ, Zindell R, McNeil D, Bekkali Y, Girardot M, Hrapchak M, DeTuri M, Crane K, White D, Pav S, Wang Y, Hao MH, Grygon CA, Labadia ME, Freeman DM, Davidson W, Hopkins JL, Brown ML, Spero DM. Ward YD, et al. Among authors: emmanuel mj. J Med Chem. 2002 Dec 5;45(25):5471-82. doi: 10.1021/jm020209i. J Med Chem. 2002. PMID: 12459015
Rapid, sensitive and efficient HPLC assays for HIV-1 proteinase.
Betageri R, Hopkins JL, Thibeault D, Emmanuel MJ, Chow GC, Skoog MT, de Dreu P, Cohen KA. Betageri R, et al. Among authors: emmanuel mj. J Biochem Biophys Methods. 1993 Oct;27(3):191-7. doi: 10.1016/0165-022x(93)90003-7. J Biochem Biophys Methods. 1993. PMID: 8258639
The discovery of carboline analogs as potent MAPKAP-K2 inhibitors.
Wu JP, Wang J, Abeywardane A, Andersen D, Emmanuel M, Gautschi E, Goldberg DR, Kashem MA, Lukas S, Mao W, Martin L, Morwick T, Moss N, Pargellis C, Patel UR, Patnaude L, Peet GW, Skow D, Snow RJ, Ward Y, Werneburg B, White A. Wu JP, et al. Among authors: emmanuel m. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4664-9. doi: 10.1016/j.bmcl.2007.05.101. Epub 2007 Jun 7. Bioorg Med Chem Lett. 2007. PMID: 17576063
Observing the crack tip behavior at the nanoscale during fracture of ceramics.
Gavalda-Diaz O, Emmanuel M, Berenov A, Marquardt K, Saiz E, Giuliani F. Gavalda-Diaz O, et al. Among authors: emmanuel m. Proc Natl Acad Sci U S A. 2024 Oct 22;121(43):e2408292121. doi: 10.1073/pnas.2408292121. Epub 2024 Oct 17. Proc Natl Acad Sci U S A. 2024. PMID: 39418311 Free PMC article.
Editorial: Vulnerability and resilience in small island developing states.
Campbell MH, Emmanuel MK, Greaves NS, Lashley M. Campbell MH, et al. Among authors: emmanuel mk. Front Psychiatry. 2024 Sep 25;15:1494503. doi: 10.3389/fpsyt.2024.1494503. eCollection 2024. Front Psychiatry. 2024. PMID: 39386894 Free PMC article. No abstract available.
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