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Alzheimer's disease susceptibility genes APOE and TOMM40, and brain white matter integrity in the Lothian Birth Cohort 1936.
Lyall DM, Harris SE, Bastin ME, Muñoz Maniega S, Murray C, Lutz MW, Saunders AM, Roses AD, Valdés Hernández Mdel C, Royle NA, Starr JM, Porteous DJ, Wardlaw JM, Deary IJ. Lyall DM, et al. Among authors: saunders am. Neurobiol Aging. 2014 Jun;35(6):1513.e25-33. doi: 10.1016/j.neurobiolaging.2014.01.006. Epub 2014 Jan 8. Neurobiol Aging. 2014. PMID: 24508314 Free PMC article.
Genetic variation at a single locus and age of onset for Alzheimer's disease.
Lutz MW, Crenshaw DG, Saunders AM, Roses AD. Lutz MW, et al. Among authors: saunders am. Alzheimers Dement. 2010 Mar;6(2):125-31. doi: 10.1016/j.jalz.2010.01.011. Alzheimers Dement. 2010. PMID: 20298972 Free PMC article.
The significant finding discussed here is that a variable-length, deoxythymidine homopolymer (poly-T) within intron 6 of the TOMM40 gene is associated with the age of onset of LOAD [Roses AD, Lutz MW, Amrine-Madsen H, Saunders AM, Crenshaw DG, Sundseth SS, et al. A …
The significant finding discussed here is that a variable-length, deoxythymidine homopolymer (poly-T) within intron 6 of the TOMM40 gene is …
Alzheimer's disease susceptibility genes APOE and TOMM40, and hippocampal volumes in the Lothian birth cohort 1936.
Lyall DM, Royle NA, Harris SE, Bastin ME, Maniega SM, Murray C, Lutz MW, Saunders AM, Roses AD, del Valdés Hernández MC, Starr JM, Porteous DJ, Wardlaw JM, Deary IJ. Lyall DM, et al. Among authors: saunders am. PLoS One. 2013 Nov 15;8(11):e80513. doi: 10.1371/journal.pone.0080513. eCollection 2013. PLoS One. 2013. PMID: 24260406 Free PMC article.
APOE/TOMM40 genetic loci, white matter hyperintensities, and cerebral microbleeds.
Lyall DM, Muñoz Maniega S, Harris SE, Bastin ME, Murray C, Lutz MW, Saunders AM, Roses AD, Valdés Hernández Mdel C, Royle NA, Starr JM, Porteous DJ, Deary IJ, Wardlaw JM. Lyall DM, et al. Among authors: saunders am. Int J Stroke. 2015 Dec;10(8):1297-300. doi: 10.1111/ijs.12615. Epub 2015 Aug 26. Int J Stroke. 2015. PMID: 26310205 Free PMC article.
Are APOE ɛ genotype and TOMM40 poly-T repeat length associations with cognitive ageing mediated by brain white matter tract integrity?
Lyall DM, Harris SE, Bastin ME, Muñoz Maniega S, Murray C, Lutz MW, Saunders AM, Roses AD, Valdés Hernández Mdel C, Royle NA, Starr JM, Porteous DJ, Wardlaw JM, Deary IJ. Lyall DM, et al. Among authors: saunders am. Transl Psychiatry. 2014 Sep 23;4(9):e449. doi: 10.1038/tp.2014.89. Transl Psychiatry. 2014. PMID: 25247594 Free PMC article.
284 results