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Patients with colorectal tumors with microsatellite instability and large deletions in HSP110 T17 have improved response to 5-fluorouracil–based chemotherapy.
Collura A, Lagrange A, Svrcek M, Marisa L, Buhard O, Guilloux A, Wanherdrick K, Dorard C, Taieb A, Saget A, Loh M, Soong R, Zeps N, Platell C, Mews A, Iacopetta B, De Thonel A, Seigneuric R, Marcion G, Chapusot C, Lepage C, Bouvier AM, Gaub MP, Milano G, Selves J, Senet P, Delarue P, Arzouk H, Lacoste C, Coquelle A, Bengrine-Lefèvre L, Tournigand C, Lefèvre JH, Parc Y, Biard DS, Fléjou JF, Garrido C, Duval A. Collura A, et al. Among authors: garrido c. Gastroenterology. 2014 Feb;146(2):401-11.e1. doi: 10.1053/j.gastro.2013.10.054. Gastroenterology. 2014. PMID: 24512910
Expression of a mutant HSP110 sensitizes colorectal cancer cells to chemotherapy and improves disease prognosis.
Dorard C, de Thonel A, Collura A, Marisa L, Svrcek M, Lagrange A, Jego G, Wanherdrick K, Joly AL, Buhard O, Gobbo J, Penard-Lacronique V, Zouali H, Tubacher E, Kirzin S, Selves J, Milano G, Etienne-Grimaldi MC, Bengrine-Lefèvre L, Louvet C, Tournigand C, Lefèvre JH, Parc Y, Tiret E, Fléjou JF, Gaub MP, Garrido C, Duval A. Dorard C, et al. Among authors: garrido c. Nat Med. 2011 Sep 25;17(10):1283-9. doi: 10.1038/nm.2457. Nat Med. 2011. PMID: 21946539
HSP110 T17 simplifies and improves the microsatellite instability testing in patients with colorectal cancer.
Buhard O, Lagrange A, Guilloux A, Colas C, Chouchène M, Wanherdrick K, Coulet F, Guillerm E, Dorard C, Marisa L, Bokhari A, Greene M, El-Murr N, Bodo S, Muleris M, Sourouille I, Svrcek M, Cervera P, Blanché H, Lefevre JH, Parc Y, Lepage C, Chapusot C, Bouvier AM, Gaub MP, Selves J, Garrett K, Iacopetta B, Soong R, Hamelin R, Garrido C, Lascols O, André T, Fléjou JF, Collura A, Duval A. Buhard O, et al. Among authors: garrido c. J Med Genet. 2016 Jun;53(6):377-84. doi: 10.1136/jmedgenet-2015-103518. Epub 2016 Feb 1. J Med Genet. 2016. PMID: 26831756
HSP110 promotes colorectal cancer growth through STAT3 activation.
Berthenet K, Bokhari A, Lagrange A, Marcion G, Boudesco C, Causse S, De Thonel A, Svrcek M, Goloudina AR, Dumont S, Hammann A, Biard DS, Demidov ON, Seigneuric R, Duval A, Collura A, Jego G, Garrido C. Berthenet K, et al. Among authors: garrido c. Oncogene. 2017 Apr 20;36(16):2328-2336. doi: 10.1038/onc.2016.403. Epub 2016 Nov 7. Oncogene. 2017. PMID: 27819670
[Mutation of HSP110 in colorectal cancer: the chaperone paradox].
Garrido C, Collura A, Berthenet K, Lagrange A, Duval A. Garrido C, et al. Med Sci (Paris). 2012 Jan;28(1):9-10. doi: 10.1051/medsci/2012281002. Epub 2012 Jan 27. Med Sci (Paris). 2012. PMID: 22289816 Free article. French. No abstract available.
Extracellular HSP110 skews macrophage polarization in colorectal cancer.
Berthenet K, Boudesco C, Collura A, Svrcek M, Richaud S, Hammann A, Causse S, Yousfi N, Wanherdrick K, Duplomb L, Duval A, Garrido C, Jego G. Berthenet K, et al. Among authors: garrido c. Oncoimmunology. 2016 Apr 22;5(7):e1170264. doi: 10.1080/2162402X.2016.1170264. eCollection 2016 Jul. Oncoimmunology. 2016. PMID: 27622020 Free PMC article.
Targeting cancer with peptide aptamers.
Seigneuric R, Gobbo J, Colas P, Garrido C. Seigneuric R, et al. Among authors: garrido c. Oncotarget. 2011 Jul;2(7):557-61. doi: 10.18632/oncotarget.297. Oncotarget. 2011. PMID: 21709317 Free PMC article.
HSP110 translocates to the nucleus upon genotoxic chemotherapy and promotes DNA repair in colorectal cancer cells.
Causse SZ, Marcion G, Chanteloup G, Uyanik B, Boudesco C, Grigorash BB, Douhard R, Dias AMM, Dumetier B, Dondaine L, Gozzi GJ, Moussay E, Paggetti J, Mirjolet C, de Thonel A, Dubrez L, Demidov ON, Gobbo J, Garrido C. Causse SZ, et al. Among authors: garrido c. Oncogene. 2019 Apr;38(15):2767-2777. doi: 10.1038/s41388-018-0616-2. Epub 2018 Dec 12. Oncogene. 2019. PMID: 30542121
Targeting heat shock proteins in cancer.
Jego G, Hazoumé A, Seigneuric R, Garrido C. Jego G, et al. Among authors: garrido c. Cancer Lett. 2013 May 28;332(2):275-85. doi: 10.1016/j.canlet.2010.10.014. Epub 2010 Nov 13. Cancer Lett. 2013. PMID: 21078542 Review.
554 results