Ruffoni A - Search Results

1

2-Amino-3-(phenylsulfanyl)norbornane-2-carboxylate: an appealing scaffold for the design of Rac1-Tiam1 protein-protein interaction inhibitors.

Ruffoni A, Ferri N, Bernini SK, Ricci C, Corsini A, Maffucci I, Clerici F, Contini A. Ruffoni A, et al. J Med Chem. 2014 Apr 10;57(7):2953-62. doi: 10.1021/jm401924s. Epub 2014 Feb 21. J Med Chem. 2014. PMID: 24520998

2

Identification of the first enantiopure Rac1-Tiam1 protein-protein interaction inhibitor and its optimized synthesis via phosphine free remote group directed hydroarylation.

Ruffoni A, Ferri N, Pinto A, Pellegrino S, Contini A, Clerici F. Ruffoni A, et al. Medchemcomm. 2018 Dec 26;10(2):310-314. doi: 10.1039/c8md00477c. eCollection 2019 Feb 1. Medchemcomm. 2018. PMID: 30931091 Free PMC article.

3

Self-assembled hydrophobic Ala-Aib peptide encapsulating curcumin: a convenient system for water insoluble drugs.

Locarno S, Argentiere S, Ruffoni A, Maggioni D, Soave R, Bucci R, Erba E, Lenardi C, Gelmi ML, Clerici F. Locarno S, et al. Among authors: ruffoni a. RSC Adv. 2020 Mar 9;10(17):9964-9975. doi: 10.1039/c9ra10981a. eCollection 2020 Mar 6. RSC Adv. 2020. PMID: 35498617 Free PMC article.

4

Synthesis of Arylamines via Aminium Radicals.

Svejstrup TD, Ruffoni A, Juliá F, Aubert VM, Leonori D. Svejstrup TD, et al. Among authors: ruffoni a. Angew Chem Int Ed Engl. 2017 Nov 20;56(47):14948-14952. doi: 10.1002/anie.201708693. Epub 2017 Oct 24. Angew Chem Int Ed Engl. 2017. PMID: 28967171 Free PMC article.

5

Photoinduced decarboxylative azidation of cyclic amino acids.

Marcote DC, Street-Jeakings R, Dauncey E, Douglas JJ, Ruffoni A, Leonori D. Marcote DC, et al. Among authors: ruffoni a. Org Biomol Chem. 2019 Feb 13;17(7):1839-1842. doi: 10.1039/c8ob02702a. Org Biomol Chem. 2019. PMID: 30623963

6

Practical and regioselective amination of arenes using alkyl amines.

Ruffoni A, Juliá F, Svejstrup TD, McMillan AJ, Douglas JJ, Leonori D. Ruffoni A, et al. Nat Chem. 2019 May;11(5):426-433. doi: 10.1038/s41557-019-0254-5. Epub 2019 Apr 22. Nat Chem. 2019. PMID: 31011173

7

Divergent Strain-Release Amino-Functionalization of [1.1.1]Propellane with Electrophilic Nitrogen-Radicals.

Kim JH, Ruffoni A, Al-Faiyz YSS, Sheikh NS, Leonori D. Kim JH, et al. Among authors: ruffoni a. Angew Chem Int Ed Engl. 2020 May 18;59(21):8225-8231. doi: 10.1002/anie.202000140. Epub 2020 Feb 26. Angew Chem Int Ed Engl. 2020. PMID: 32003916 Free PMC article.

8

Practical and Selective sp³ C-H Bond Chlorination via Aminium Radicals.

McMillan AJ, Sieńkowska M, Di Lorenzo P, Gransbury GK, Chilton NF, Salamone M, Ruffoni A, Bietti M, Leonori D. McMillan AJ, et al. Among authors: ruffoni a. Angew Chem Int Ed Engl. 2021 Mar 22;60(13):7132-7139. doi: 10.1002/anie.202100030. Epub 2021 Feb 25. Angew Chem Int Ed Engl. 2021. PMID: 33458924 Free PMC article.

9

Photoexcited nitroarenes for the oxidative cleavage of alkenes.

Ruffoni A, Hampton C, Simonetti M, Leonori D. Ruffoni A, et al. Nature. 2022 Oct;610(7930):81-86. doi: 10.1038/s41586-022-05211-0. Epub 2022 Aug 23. Nature. 2022. PMID: 35998666

10

Direct synthesis of fluorinated heteroarylether bioisosteres.

Zhou Q, Ruffoni A, Gianatassio R, Fujiwara Y, Sella E, Shabat D, Baran PS. Zhou Q, et al. Among authors: ruffoni a. Angew Chem Int Ed Engl. 2013 Apr 2;52(14):3949-52. doi: 10.1002/anie.201300763. Epub 2013 Mar 4. Angew Chem Int Ed Engl. 2013. PMID: 23460402 Free PMC article.

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