Lack of a C-terminal tail in the mammalian gonadotropin-releasing hormone receptor confers resistance to agonist-dependent phosphorylation and rapid desensitization.
Willars GB, Heding A, Vrecl M, Sellar R, Blomenröhr M, Nahorski SR, Eidne KA.
Willars GB, et al. Among authors: eidne ka.
J Biol Chem. 1999 Oct 15;274(42):30146-53. doi: 10.1074/jbc.274.42.30146.
J Biol Chem. 1999.
PMID: 10514504
Free article.
We have previously demonstrated that this unique structural feature is associated with resistance to rapid desensitization of phosphoinositide signaling in COS-7 and HEK-293 cells (Heding, A., Vrecl, M., Bogerd, J., McGregor, A., Sellar, R., Taylor, P. L., and Eidne, K …
We have previously demonstrated that this unique structural feature is associated with resistance to rapid desensitization of phosphoinositi …