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Page 1
Discovery of compounds blocking the proliferation of Toxoplasma gondii and Plasmodium falciparum in a chemical space based on piperidinyl-benzimidazolone analogs.
Saïdani N, Botté CY, Deligny M, Bonneau AL, Reader J, Lasselin R, Merer G, Niepceron A, Brossier F, Cintrat JC, Rousseau B, Birkholtz LM, Cesbron-Delauw MF, Dubremetz JF, Mercier C, Vial H, Lopez R, Maréchal E. Saïdani N, et al. Among authors: merer g. Antimicrob Agents Chemother. 2014 May;58(5):2586-97. doi: 10.1128/AAC.01445-13. Epub 2014 Feb 18. Antimicrob Agents Chemother. 2014. PMID: 24550329 Free PMC article.
Small-molecule inhibitors of sodium iodide symporter function.
Lecat-Guillet N, Merer G, Lopez R, Pourcher T, Rousseau B, Ambroise Y. Lecat-Guillet N, et al. Among authors: merer g. Chembiochem. 2008 Apr 14;9(6):889-95. doi: 10.1002/cbic.200700682. Chembiochem. 2008. PMID: 18307189
ABMA, a small molecule that inhibits intracellular toxins and pathogens by interfering with late endosomal compartments.
Wu Y, Pons V, Goudet A, Panigai L, Fischer A, Herweg JA, Kali S, Davey RA, Laporte J, Bouclier C, Yousfi R, Aubenque C, Merer G, Gobbo E, Lopez R, Gillet C, Cojean S, Popoff MR, Clayette P, Le Grand R, Boulogne C, Tordo N, Lemichez E, Loiseau PM, Rudel T, Sauvaire D, Cintrat JC, Gillet D, Barbier J. Wu Y, et al. Among authors: merer g. Sci Rep. 2017 Nov 14;7(1):15567. doi: 10.1038/s41598-017-15466-7. Sci Rep. 2017. PMID: 29138439 Free PMC article.
Inhibition of retrograde transport protects mice from lethal ricin challenge.
Stechmann B, Bai SK, Gobbo E, Lopez R, Merer G, Pinchard S, Panigai L, Tenza D, Raposo G, Beaumelle B, Sauvaire D, Gillet D, Johannes L, Barbier J. Stechmann B, et al. Among authors: merer g. Cell. 2010 Apr 16;141(2):231-42. doi: 10.1016/j.cell.2010.01.043. Cell. 2010. PMID: 20403321 Free article.