Quintás-Cardama A - Search Results

1

Molecular dynamics reveal BCR-ABL1 polymutants as a unique mechanism of resistance to PAN-BCR-ABL1 kinase inhibitor therapy.

Gibbons DL, Pricl S, Posocco P, Laurini E, Fermeglia M, Sun H, Talpaz M, Donato N, Quintás-Cardama A. Gibbons DL, et al. Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3550-5. doi: 10.1073/pnas.1321173111. Epub 2014 Feb 18. Proc Natl Acad Sci U S A. 2014. PMID: 24550512 Free PMC article.

2

The rise and fall of gatekeeper mutations? The BCR-ABL1 T315I paradigm.

Gibbons DL, Pricl S, Kantarjian H, Cortes J, Quintás-Cardama A. Gibbons DL, et al. Cancer. 2012 Jan 15;118(2):293-9. doi: 10.1002/cncr.26225. Epub 2011 Jul 5. Cancer. 2012. PMID: 21732333 Free PMC article.

3

Dasatinib (BMS-354825) is active in Philadelphia chromosome-positive chronic myelogenous leukemia after imatinib and nilotinib (AMN107) therapy failure.

Quintas-Cardama A, Kantarjian H, Jones D, Nicaise C, O'Brien S, Giles F, Talpaz M, Cortes J. Quintas-Cardama A, et al. Blood. 2007 Jan 15;109(2):497-9. doi: 10.1182/blood-2006-07-035493. Epub 2006 Sep 21. Blood. 2007. PMID: 16990591 Free article. Clinical Trial.

4

Through the open door: Preferential binding of dasatinib to the active form of BCR-ABL unveiled by in silico experiments.

Laurini E, Posocco P, Fermeglia M, Gibbons DL, Quintás-Cardama A, Pricl S. Laurini E, et al. Mol Oncol. 2013 Oct;7(5):968-75. doi: 10.1016/j.molonc.2013.06.001. Epub 2013 Jun 15. Mol Oncol. 2013. PMID: 23816609 Free PMC article.

5

Sequencing of subcloned PCR products facilitates earlier detection of BCR-ABL1(T315I) and other mutants compared to direct sequencing of the ABL1 kinase domain.

Quintás-Cardama A, Gibbons DL, Kantarjian H, Talpaz M, Donato N, Cortes J. Quintás-Cardama A, et al. Leukemia. 2008 Apr;22(4):885-8. doi: 10.1038/leu.2008.42. Epub 2008 Feb 28. Leukemia. 2008. PMID: 18305550 No abstract available.

6

Imatinib mesylate therapy may overcome the poor prognostic significance of deletions of derivative chromosome 9 in patients with chronic myelogenous leukemia.

Quintas-Cardama A, Kantarjian H, Talpaz M, O'Brien S, Garcia-Manero G, Verstovsek S, Rios MB, Hayes K, Glassman A, Bekele BN, Zhou X, Cortes J. Quintas-Cardama A, et al. Blood. 2005 Mar 15;105(6):2281-6. doi: 10.1182/blood-2004-06-2208. Epub 2004 Nov 30. Blood. 2005. PMID: 15572595 Free article. Clinical Trial.

7

Improved survival in chronic myeloid leukemia since the introduction of imatinib therapy: a single-institution historical experience.

Kantarjian H, O'Brien S, Jabbour E, Garcia-Manero G, Quintas-Cardama A, Shan J, Rios MB, Ravandi F, Faderl S, Kadia T, Borthakur G, Huang X, Champlin R, Talpaz M, Cortes J. Kantarjian H, et al. Blood. 2012 Mar 1;119(9):1981-7. doi: 10.1182/blood-2011-08-358135. Epub 2012 Jan 6. Blood. 2012. PMID: 22228624 Free PMC article.

8

Granulocyte-colony-stimulating factor (filgrastim) may overcome imatinib-induced neutropenia in patients with chronic-phase chronic myelogenous leukemia.

Quintas-Cardama A, Kantarjian H, O'Brien S, Garcia-Manero G, Rios MB, Talpaz M, Cortes J. Quintas-Cardama A, et al. Cancer. 2004 Jun 15;100(12):2592-7. doi: 10.1002/cncr.20285. Cancer. 2004. PMID: 15197801 Free article.

9

ON012380, a putative BCR-ABL kinase inhibitor with a unique mechanism of action in imatinib-resistant cells.

Wu J, Meng F, Ying Y, Peng Z, Daniels L, Bornmann WG, Quintás-Cardama A, Roulston D, Talpaz M, Peterson LF, Donato NJ. Wu J, et al. Leukemia. 2010 Apr;24(4):869-72. doi: 10.1038/leu.2009.300. Epub 2010 Jan 28. Leukemia. 2010. PMID: 20111070 Free PMC article. No abstract available.

10

Re-emergence of interferon-α in the treatment of chronic myeloid leukemia.

Talpaz M, Hehlmann R, Quintás-Cardama A, Mercer J, Cortes J. Talpaz M, et al. Leukemia. 2013 Apr;27(4):803-12. doi: 10.1038/leu.2012.313. Epub 2012 Nov 7. Leukemia. 2013. PMID: 23238589 Free PMC article. Review.

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