Muñoz-Torrero D - Search Results

1

Synthesis and multitarget biological profiling of a novel family of rhein derivatives as disease-modifying anti-Alzheimer agents.

Viayna E, Sola I, Bartolini M, De Simone A, Tapia-Rojas C, Serrano FG, Sabaté R, Juárez-Jiménez J, Pérez B, Luque FJ, Andrisano V, Clos MV, Inestrosa NC, Muñoz-Torrero D. Viayna E, et al. J Med Chem. 2014 Mar 27;57(6):2549-67. doi: 10.1021/jm401824w. Epub 2014 Mar 10. J Med Chem. 2014. PMID: 24568372 Free article.

2

Synthesis and evaluation of tacrine-huperzine A hybrids as acetylcholinesterase inhibitors of potential interest for the treatment of Alzheimer's disease.

Badia A, Baños JE, Camps P, Contreras J, Görbig DM, Muñoz-Torrero D, Simón M, Vivas NM. Badia A, et al. Bioorg Med Chem. 1998 Apr;6(4):427-40. doi: 10.1016/s0968-0896(98)00015-7. Bioorg Med Chem. 1998. PMID: 9597187

3

Synthesis, in vitro pharmacology, and molecular modeling of very potent tacrine-huperzine A hybrids as acetylcholinesterase inhibitors of potential interest for the treatment of Alzheimer's disease.

Camps P, El Achab R, Görbig DM, Morral J, Muñoz-Torrero D, Badia A, Eladi Baños J, Vivas NM, Barril X, Orozco M, Luque FJ. Camps P, et al. J Med Chem. 1999 Aug 26;42(17):3227-42. doi: 10.1021/jm980620z. J Med Chem. 1999. PMID: 10464010

4

New tacrine-huperzine A hybrids (huprines): highly potent tight-binding acetylcholinesterase inhibitors of interest for the treatment of Alzheimer's disease.

Camps P, El Achab R, Morral J, Muñoz-Torrero D, Badia A, Baños JE, Vivas NM, Barril X, Orozco M, Luque FJ. Camps P, et al. J Med Chem. 2000 Nov 30;43(24):4657-66. doi: 10.1021/jm000980y. J Med Chem. 2000. PMID: 11101357

5

Synthesis, in vitro pharmacology, and molecular modeling of syn-huprines as acetylcholinesterase inhibitors.

Camps P, Gómez E, Muñoz-Torrero D, Badia A, Vivas NM, Barril X, Orozco M, Luque FJ. Camps P, et al. J Med Chem. 2001 Dec 20;44(26):4733-6. doi: 10.1021/jm010949b. J Med Chem. 2001. PMID: 11741490

6

Cholinergic drugs in pharmacotherapy of Alzheimer's disease.

Camps P, Muñoz-Torrero D. Camps P, et al. Mini Rev Med Chem. 2002 Feb;2(1):11-25. doi: 10.2174/1389557023406638. Mini Rev Med Chem. 2002. PMID: 12369954 Review.

7

Tacrine-huperzine A hybrids (huprines): a new class of highly potent and selective acetylcholinesterase inhibitors of interest for the treatment of Alzheimer's disease.

Camps P, Muñoz-Torrero D. Camps P, et al. Mini Rev Med Chem. 2001 Jul;1(2):163-74. doi: 10.2174/1389557013406972. Mini Rev Med Chem. 2001. PMID: 12369981 Review.

8

Synthesis and pharmacological evaluation of huprine-tacrine heterodimers: subnanomolar dual binding site acetylcholinesterase inhibitors.

Camps P, Formosa X, Muñoz-Torrero D, Petrignet J, Badia A, Clos MV. Camps P, et al. J Med Chem. 2005 Mar 24;48(6):1701-4. doi: 10.1021/jm0496741. J Med Chem. 2005. PMID: 15771413

9

Effects of (+/-)-huprine Y and (+/-)-huprine Z, two new anticholinesterasic drugs, on muscarinic receptors.

Alcalá MM, Maderuelo A, Vivas NM, Camps P, Muñoz-Torrero D, Clos MV, Badia A. Alcalá MM, et al. Neurosci Lett. 2005 May 6;379(2):106-9. doi: 10.1016/j.neulet.2004.12.044. Epub 2005 Jan 20. Neurosci Lett. 2005. PMID: 15823425

10

Nicotinic-receptor potentiator drugs, huprine X and galantamine, increase ACh release by blocking AChE activity but not acting on nicotinic receptors.

Roman S, Badia A, Camps P, Muñoz-Torrero D, Clos MV. Roman S, et al. Brain Res. 2005 Nov 9;1061(2):73-9. doi: 10.1016/j.brainres.2005.07.042. Epub 2005 Oct 24. Brain Res. 2005. PMID: 16248990

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