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DLX5, FGF8 and the Pin1 isomerase control ΔNp63α protein stability during limb development: a regulatory loop at the basis of the SHFM and EEC congenital malformations.
Restelli M, Lopardo T, Lo Iacono N, Garaffo G, Conte D, Rustighi A, Napoli M, Del Sal G, Perez-Morga D, Costanzo A, Merlo GR, Guerrini L. Restelli M, et al. Among authors: guerrini l. Hum Mol Genet. 2014 Jul 15;23(14):3830-42. doi: 10.1093/hmg/ddu096. Epub 2014 Feb 25. Hum Mol Genet. 2014. PMID: 24569166 Free PMC article.
A regulatory feedback loop involving p63 and IRF6 links the pathogenesis of 2 genetically different human ectodermal dysplasias.
Moretti F, Marinari B, Lo Iacono N, Botti E, Giunta A, Spallone G, Garaffo G, Vernersson-Lindahl E, Merlo G, Mills AA, Ballarò C, Alemà S, Chimenti S, Guerrini L, Costanzo A. Moretti F, et al. Among authors: guerrini l. J Clin Invest. 2010 May;120(5):1570-7. doi: 10.1172/JCI40267. Epub 2010 Apr 26. J Clin Invest. 2010. PMID: 20424325 Free PMC article.
197 results