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β-Catenin promotes colitis and colon cancer through imprinting of proinflammatory properties in T cells.
Keerthivasan S, Aghajani K, Dose M, Molinero L, Khan MW, Venkateswaran V, Weber C, Emmanuel AO, Sun T, Bentrem DJ, Mulcahy M, Keshavarzian A, Ramos EM, Blatner N, Khazaie K, Gounari F. Keerthivasan S, et al. Among authors: khazaie k. Sci Transl Med. 2014 Feb 26;6(225):225ra28. doi: 10.1126/scitranslmed.3007607. Sci Transl Med. 2014. PMID: 24574339 Free PMC article.
Expression of RORγt marks a pathogenic regulatory T cell subset in human colon cancer.
Blatner NR, Mulcahy MF, Dennis KL, Scholtens D, Bentrem DJ, Phillips JD, Ham S, Sandall BP, Khan MW, Mahvi DM, Halverson AL, Stryker SJ, Boller AM, Singal A, Sneed RK, Sarraj B, Ansari MJ, Oft M, Iwakura Y, Zhou L, Bonertz A, Beckhove P, Gounari F, Khazaie K. Blatner NR, et al. Among authors: khazaie k. Sci Transl Med. 2012 Dec 12;4(164):164ra159. doi: 10.1126/scitranslmed.3004566. Sci Transl Med. 2012. PMID: 23241743 Free PMC article.
Wnt-β-catenin activation epigenetically reprograms Treg cells in inflammatory bowel disease and dysplastic progression.
Quandt J, Arnovitz S, Haghi L, Woehlk J, Mohsin A, Okoreeh M, Mathur PS, Emmanuel AO, Osman A, Krishnan M, Morin SB, Pearson AT, Sweis RF, Pekow J, Weber CR, Khazaie K, Gounari F. Quandt J, et al. Among authors: khazaie k. Nat Immunol. 2021 Apr;22(4):471-484. doi: 10.1038/s41590-021-00889-2. Epub 2021 Mar 4. Nat Immunol. 2021. PMID: 33664518 Free PMC article.
The significant role of mast cells in cancer.
Khazaie K, Blatner NR, Khan MW, Gounari F, Gounaris E, Dennis K, Bonertz A, Tsai FN, Strouch MJ, Cheon E, Phillips JD, Beckhove P, Bentrem DJ. Khazaie K, et al. Cancer Metastasis Rev. 2011 Mar;30(1):45-60. doi: 10.1007/s10555-011-9286-z. Cancer Metastasis Rev. 2011. PMID: 21287360 Review.
PI3K/AKT signaling is essential for communication between tissue-infiltrating mast cells, macrophages, and epithelial cells in colitis-induced cancer.
Khan MW, Keshavarzian A, Gounaris E, Melson JE, Cheon EC, Blatner NR, Chen ZE, Tsai FN, Lee G, Ryu H, Barrett TA, Bentrem DJ, Beckhove P, Khazaie K. Khan MW, et al. Among authors: khazaie k. Clin Cancer Res. 2013 May 1;19(9):2342-54. doi: 10.1158/1078-0432.CCR-12-2623. Epub 2013 Mar 13. Clin Cancer Res. 2013. PMID: 23487439 Free PMC article.
The two faces of regulatory T cells in cancer.
Blatner NR, Gounari F, Khazaie K. Blatner NR, et al. Among authors: khazaie k. Oncoimmunology. 2013 May 1;2(5):e23852. doi: 10.4161/onci.23852. Epub 2013 Apr 15. Oncoimmunology. 2013. PMID: 23762787 Free PMC article.
129 results