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Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder.
Grubman A, Lidgerwood GE, Duncan C, Bica L, Tan JL, Parker SJ, Caragounis A, Meyerowitz J, Volitakis I, Moujalled D, Liddell JR, Hickey JL, Horne M, Longmuir S, Koistinaho J, Donnelly PS, Crouch PJ, Tammen I, White AR, Kanninen KM. Grubman A, et al. Among authors: koistinaho j. Acta Neuropathol Commun. 2014 Feb 28;2:25. doi: 10.1186/2051-5960-2-25. Acta Neuropathol Commun. 2014. PMID: 24581221 Free PMC article.
Biometals in rare neurodegenerative disorders of childhood.
Parker SJ, Koistinaho J, White AR, Kanninen KM. Parker SJ, et al. Among authors: koistinaho j. Front Aging Neurosci. 2013 Mar 25;5:14. doi: 10.3389/fnagi.2013.00014. eCollection 2013. Front Aging Neurosci. 2013. PMID: 23531702 Free PMC article.
Applications of the Keap1-Nrf2 system for gene and cell therapy.
Kanninen KM, Pomeshchik Y, Leinonen H, Malm T, Koistinaho J, Levonen AL. Kanninen KM, et al. Among authors: koistinaho j. Free Radic Biol Med. 2015 Nov;88(Pt B):350-361. doi: 10.1016/j.freeradbiomed.2015.06.037. Epub 2015 Jul 8. Free Radic Biol Med. 2015. PMID: 26164630 Review.
Exosomes as new diagnostic tools in CNS diseases.
Kanninen KM, Bister N, Koistinaho J, Malm T. Kanninen KM, et al. Among authors: koistinaho j. Biochim Biophys Acta. 2016 Mar;1862(3):403-10. doi: 10.1016/j.bbadis.2015.09.020. Epub 2015 Oct 20. Biochim Biophys Acta. 2016. PMID: 26432482 Free article. Review. No abstract available.
Pyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytes.
Liddell JR, Lehtonen S, Duncan C, Keksa-Goldsteine V, Levonen AL, Goldsteins G, Malm T, White AR, Koistinaho J, Kanninen KM. Liddell JR, et al. Among authors: koistinaho j. J Neuroinflammation. 2016 Feb 26;13:49. doi: 10.1186/s12974-016-0515-9. J Neuroinflammation. 2016. PMID: 26920699 Free PMC article.
The Copper bis(thiosemicarbazone) Complex CuII(atsm) Is Protective Against Cerebral Ischemia Through Modulation of the Inflammatory Milieu.
Huuskonen MT, Tuo QZ, Loppi S, Dhungana H, Korhonen P, McInnes LE, Donnelly PS, Grubman A, Wojciechowski S, Lejavova K, Pomeshchik Y, Periviita L, Kosonen L, Giordano M, Walker FR, Liu R, Bush AI, Koistinaho J, Malm T, White AR, Lei P, Kanninen KM. Huuskonen MT, et al. Among authors: koistinaho j. Neurotherapeutics. 2017 Apr;14(2):519-532. doi: 10.1007/s13311-016-0504-9. Neurotherapeutics. 2017. PMID: 28050710 Free PMC article.
Loss of Cln5 causes altered neurogenesis in a mouse model of a childhood neurodegenerative disorder.
Savchenko E, Singh Y, Konttinen H, Lejavova K, Mediavilla Santos L, Grubman A, Kärkkäinen V, Keksa-Goldsteine V, Naumenko N, Tavi P, White AR, Malm T, Koistinaho J, Kanninen KM. Savchenko E, et al. Among authors: koistinaho j. Dis Model Mech. 2017 Sep 1;10(9):1089-1100. doi: 10.1242/dmm.029165. Epub 2017 Jul 21. Dis Model Mech. 2017. PMID: 28733362 Free PMC article.
290 results