Tong Q - Search Results

1

Target-selective phototherapy using a ligand-based photosensitizer for type 2 cannabinoid receptor.

Zhang S, Jia N, Shao P, Tong Q, Xie XQ, Bai M. Zhang S, et al. Among authors: tong q. Chem Biol. 2014 Mar 20;21(3):338-44. doi: 10.1016/j.chembiol.2014.01.009. Epub 2014 Feb 27. Chem Biol. 2014. PMID: 24583052 Free PMC article.

2

Novel triaryl sulfonamide derivatives as selective cannabinoid receptor 2 inverse agonists and osteoclast inhibitors: discovery, optimization, and biological evaluation.

Yang P, Wang L, Feng R, Almehizia AA, Tong Q, Myint KZ, Ouyang Q, Alqarni MH, Wang L, Xie XQ. Yang P, et al. Among authors: tong q. J Med Chem. 2013 Mar 14;56(5):2045-58. doi: 10.1021/jm3017464. Epub 2013 Mar 1. J Med Chem. 2013. PMID: 23406429 Free PMC article.

3

Mistic and TarCF as fusion protein partners for functional expression of the cannabinoid receptor 2 in Escherichia coli.

Chowdhury A, Feng R, Tong Q, Zhang Y, Xie XQ. Chowdhury A, et al. Among authors: tong q. Protein Expr Purif. 2012 Jun;83(2):128-34. doi: 10.1016/j.pep.2012.01.008. Epub 2012 Mar 3. Protein Expr Purif. 2012. PMID: 22406258 Free PMC article.

4

Molecular fingerprint-based artificial neural networks QSAR for ligand biological activity predictions.

Myint KZ, Wang L, Tong Q, Xie XQ. Myint KZ, et al. Among authors: tong q. Mol Pharm. 2012 Oct 1;9(10):2912-23. doi: 10.1021/mp300237z. Epub 2012 Aug 31. Mol Pharm. 2012. PMID: 22937990 Free PMC article.

5

Lead discovery, chemistry optimization, and biological evaluation studies of novel biamide derivatives as CB2 receptor inverse agonists and osteoclast inhibitors.

Yang P, Myint KZ, Tong Q, Feng R, Cao H, Almehizia AA, Alqarni MH, Wang L, Bartlow P, Gao Y, Gertsch J, Teramachi J, Kurihara N, Roodman GD, Cheng T, Xie XQ. Yang P, et al. Among authors: tong q. J Med Chem. 2012 Nov 26;55(22):9973-87. doi: 10.1021/jm301212u. Epub 2012 Oct 31. J Med Chem. 2012. PMID: 23072339 Free PMC article.

6

Trisubstituted Sulfonamides: a New Chemotype for Development of Potent and Selective CB₂ Receptor Inverse Agonists.

Ouyang Q, Tong Q, Feng R, Myint KZ, Yang P, Xie XQ. Ouyang Q, et al. Among authors: tong q. ACS Med Chem Lett. 2013 Apr 11;4(4):387-392. doi: 10.1021/ml3004236. ACS Med Chem Lett. 2013. PMID: 24729834 Free PMC article.

7

Modeling, molecular dynamics simulation, and mutation validation for structure of cannabinoid receptor 2 based on known crystal structures of GPCRs.

Feng Z, Alqarni MH, Yang P, Tong Q, Chowdhury A, Wang L, Xie XQ. Feng Z, et al. Among authors: tong q. J Chem Inf Model. 2014 Sep 22;54(9):2483-99. doi: 10.1021/ci5002718. Epub 2014 Sep 5. J Chem Inf Model. 2014. PMID: 25141027 Free PMC article.

8

Examining the critical roles of human CB2 receptor residues Valine 3.32 (113) and Leucine 5.41 (192) in ligand recognition and downstream signaling activities.

Alqarni M, Myint KZ, Tong Q, Yang P, Bartlow P, Wang L, Feng R, Xie XQ. Alqarni M, et al. Among authors: tong q. Biochem Biophys Res Commun. 2014 Sep 26;452(3):334-9. doi: 10.1016/j.bbrc.2014.08.048. Epub 2014 Aug 19. Biochem Biophys Res Commun. 2014. PMID: 25148941 Free PMC article.

9

Targeting cannabinoid receptor-2 pathway by phenylacetylamide suppresses the proliferation of human myeloma cells through mitotic dysregulation and cytoskeleton disruption.

Feng R, Tong Q, Xie Z, Cheng H, Wang L, Lentzsch S, Roodman GD, Xie XQ. Feng R, et al. Among authors: tong q. Mol Carcinog. 2015 Dec;54(12):1796-806. doi: 10.1002/mc.22251. Epub 2015 Jan 16. Mol Carcinog. 2015. PMID: 25640641 Free PMC article.

10

Difference and Influence of Inactive and Active States of Cannabinoid Receptor Subtype CB2: From Conformation to Drug Discovery.

Hu J, Feng Z, Ma S, Zhang Y, Tong Q, Alqarni MH, Gou X, Xie XQ. Hu J, et al. Among authors: tong q. J Chem Inf Model. 2016 Jun 27;56(6):1152-63. doi: 10.1021/acs.jcim.5b00739. Epub 2016 May 26. J Chem Inf Model. 2016. PMID: 27186994 Free PMC article.

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