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Efficient in vivo deletion of a large imprinted lncRNA by CRISPR/Cas9.
Han J, Zhang J, Chen L, Shen B, Zhou J, Hu B, Du Y, Tate PH, Huang X, Zhang W. Han J, et al. Among authors: zhang w, zhang j. RNA Biol. 2014;11(7):829-35. doi: 10.4161/rna.29624. Epub 2014 Aug 19. RNA Biol. 2014. PMID: 25137067 Free PMC article.
Off-target mutations are rare in Cas9-modified mice.
Iyer V, Shen B, Zhang W, Hodgkins A, Keane T, Huang X, Skarnes WC. Iyer V, et al. Among authors: zhang w. Nat Methods. 2015 Jun;12(6):479. doi: 10.1038/nmeth.3408. Nat Methods. 2015. PMID: 26020497 No abstract available.
Hippo-YAP signaling controls lineage differentiation of mouse embryonic stem cells through modulating the formation of super-enhancers.
Sun X, Ren Z, Cun Y, Zhao C, Huang X, Zhou J, Hu R, Su X, Ji L, Li P, Mak KLK, Gao F, Yang Y, Xu H, Ding J, Cao N, Li S, Zhang W, Lan P, Sun H, Wang J, Yuan P. Sun X, et al. Among authors: zhang w. Nucleic Acids Res. 2020 Jul 27;48(13):7182-7196. doi: 10.1093/nar/gkaa482. Nucleic Acids Res. 2020. PMID: 32510157 Free PMC article.
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