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Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.
Banerjee I, Zhang J, Moore-Morris T, Pfeiffer E, Buchholz KS, Liu A, Ouyang K, Stroud MJ, Gerace L, Evans SM, McCulloch A, Chen J. Banerjee I, et al. Among authors: stroud mj. PLoS Genet. 2014 Feb 20;10(2):e1004114. doi: 10.1371/journal.pgen.1004114. eCollection 2014 Feb. PLoS Genet. 2014. PMID: 24586179 Free PMC article.
Normalization of Naxos plakoglobin levels restores cardiac function in mice.
Zhang Z, Stroud MJ, Zhang J, Fang X, Ouyang K, Kimura K, Mu Y, Dalton ND, Gu Y, Bradford WH, Peterson KL, Cheng H, Zhou X, Chen J. Zhang Z, et al. Among authors: stroud mj. J Clin Invest. 2015 Apr;125(4):1708-12. doi: 10.1172/JCI80335. Epub 2015 Feb 23. J Clin Invest. 2015. PMID: 25705887 Free PMC article.
Adipocyte-specific loss of PPARγ attenuates cardiac hypertrophy.
Fang X, Stroud MJ, Ouyang K, Fang L, Zhang J, Dalton ND, Gu Y, Wu T, Peterson KL, Huang HD, Chen J, Wang N. Fang X, et al. Among authors: stroud mj. JCI Insight. 2016 Oct 6;1(16):e89908. doi: 10.1172/jci.insight.89908. JCI Insight. 2016. PMID: 27734035 Free PMC article.
Loss-of-function mutations in co-chaperone BAG3 destabilize small HSPs and cause cardiomyopathy.
Fang X, Bogomolovas J, Wu T, Zhang W, Liu C, Veevers J, Stroud MJ, Zhang Z, Ma X, Mu Y, Lao DH, Dalton ND, Gu Y, Wang C, Wang M, Liang Y, Lange S, Ouyang K, Peterson KL, Evans SM, Chen J. Fang X, et al. Among authors: stroud mj. J Clin Invest. 2017 Aug 1;127(8):3189-3200. doi: 10.1172/JCI94310. Epub 2017 Jul 24. J Clin Invest. 2017. PMID: 28737513 Free PMC article.
Luma is not essential for murine cardiac development and function.
Stroud MJ, Fang X, Zhang J, Guimarães-Camboa N, Veevers J, Dalton ND, Gu Y, Bradford WH, Peterson KL, Evans SM, Gerace L, Chen J. Stroud MJ, et al. Cardiovasc Res. 2018 Mar 1;114(3):378-388. doi: 10.1093/cvr/cvx205. Cardiovasc Res. 2018. PMID: 29040414 Free PMC article.
Lem2 is essential for cardiac development by maintaining nuclear integrity.
Ross JA, Arcos-Villacis N, Battey E, Boogerd C, Orellana CA, Marhuenda E, Swiatlowska P, Hodzic D, Prin F, Mohun T, Catibog N, Tapia O, Gerace L, Iskratsch T, Shah AM, Stroud MJ. Ross JA, et al. Among authors: stroud mj. Cardiovasc Res. 2023 Sep 5;119(11):2074-2088. doi: 10.1093/cvr/cvad061. Cardiovasc Res. 2023. PMID: 37067297 Free PMC article.
THE NUCLEUS: Mechanosensing in cardiac disease.
Ross JA, Stroud MJ. Ross JA, et al. Among authors: stroud mj. Int J Biochem Cell Biol. 2021 Aug;137:106035. doi: 10.1016/j.biocel.2021.106035. Epub 2021 Jul 6. Int J Biochem Cell Biol. 2021. PMID: 34242685 Free article. Review.
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