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Mechanisms of HsSAS-6 assembly promoting centriole formation in human cells.
Keller D, Orpinell M, Olivier N, Wachsmuth M, Mahen R, Wyss R, Hachet V, Ellenberg J, Manley S, Gönczy P. Keller D, et al. Among authors: orpinell m. J Cell Biol. 2014 Mar 3;204(5):697-712. doi: 10.1083/jcb.201307049. J Cell Biol. 2014. PMID: 24590172 Free PMC article.
A missense mutation in the PISA domain of HsSAS-6 causes autosomal recessive primary microcephaly in a large consanguineous Pakistani family.
Khan MA, Rupp VM, Orpinell M, Hussain MS, Altmüller J, Steinmetz MO, Enzinger C, Thiele H, Höhne W, Nürnberg G, Baig SM, Ansar M, Nürnberg P, Vincent JB, Speicher MR, Gönczy P, Windpassinger C. Khan MA, et al. Among authors: orpinell m. Hum Mol Genet. 2014 Nov 15;23(22):5940-9. doi: 10.1093/hmg/ddu318. Epub 2014 Jun 20. Hum Mol Genet. 2014. PMID: 24951542
CDK4 Phosphorylates AMPKα2 to Inhibit Its Activity and Repress Fatty Acid Oxidation.
Lopez-Mejia IC, Lagarrigue S, Giralt A, Martinez-Carreres L, Zanou N, Denechaud PD, Castillo-Armengol J, Chavey C, Orpinell M, Delacuisine B, Nasrallah A, Collodet C, Zhang L, Viollet B, Hardie DG, Fajas L. Lopez-Mejia IC, et al. Among authors: orpinell m. Mol Cell. 2017 Oct 19;68(2):336-349.e6. doi: 10.1016/j.molcel.2017.09.034. Mol Cell. 2017. PMID: 29053957 Free article.
CDK4 Regulates Lysosomal Function and mTORC1 Activation to Promote Cancer Cell Survival.
Martínez-Carreres L, Puyal J, Leal-Esteban LC, Orpinell M, Castillo-Armengol J, Giralt A, Dergai O, Moret C, Barquissau V, Nasrallah A, Pabois A, Zhang L, Romero P, Lopez-Mejia IC, Fajas L. Martínez-Carreres L, et al. Among authors: orpinell m. Cancer Res. 2019 Oct 15;79(20):5245-5259. doi: 10.1158/0008-5472.CAN-19-0708. Epub 2019 Aug 8. Cancer Res. 2019. PMID: 31395606 Free PMC article.
The nuclear cofactor DOR regulates autophagy in mammalian and Drosophila cells.
Mauvezin C, Orpinell M, Francis VA, Mansilla F, Duran J, Ribas V, Palacín M, Boya P, Teleman AA, Zorzano A. Mauvezin C, et al. Among authors: orpinell m. EMBO Rep. 2010 Jan;11(1):37-44. doi: 10.1038/embor.2009.242. Epub 2009 Dec 4. EMBO Rep. 2010. PMID: 20010805 Free PMC article.
13 results