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APC alterations are frequently involved in the pathogenesis of acinar cell carcinoma of the pancreas, mainly through gene loss and promoter hypermethylation.
Furlan D, Sahnane N, Bernasconi B, Frattini M, Tibiletti MG, Molinari F, Marando A, Zhang L, Vanoli A, Casnedi S, Adsay V, Notohara K, Albarello L, Asioli S, Sessa F, Capella C, La Rosa S. Furlan D, et al. Among authors: capella c. Virchows Arch. 2014 May;464(5):553-64. doi: 10.1007/s00428-014-1562-1. Epub 2014 Mar 4. Virchows Arch. 2014. PMID: 24590585
TP53 alterations in pancreatic acinar cell carcinoma: new insights into the molecular pathology of this rare cancer.
La Rosa S, Bernasconi B, Frattini M, Tibiletti MG, Molinari F, Furlan D, Sahnane N, Vanoli A, Albarello L, Zhang L, Notohara K, Casnedi S, Chenard MP, Adsay V, Asioli S, Capella C, Sessa F. La Rosa S, et al. Among authors: capella c. Virchows Arch. 2016 Mar;468(3):289-96. doi: 10.1007/s00428-015-1882-9. Epub 2015 Nov 19. Virchows Arch. 2016. PMID: 26586531
353 results