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Identification of allosteric inhibitors blocking the hepatitis C virus polymerase NS5B in the RNA synthesis initiation step.
Betzi S, Eydoux C, Bussetta C, Blemont M, Leyssen P, Debarnot C, Ben-Rahou M, Haiech J, Hibert M, Gueritte F, Grierson DS, Romette JL, Guillemot JC, Neyts J, Alvarez K, Morelli X, Dutartre H, Canard B. Betzi S, et al. Among authors: morelli x. Antiviral Res. 2009 Oct;84(1):48-59. doi: 10.1016/j.antiviral.2009.06.009. Epub 2009 Jul 7. Antiviral Res. 2009. PMID: 19589358
Molecular mapping of the RNA Cap 2'-O-methyltransferase activation interface between severe acute respiratory syndrome coronavirus nsp10 and nsp16.
Lugari A, Betzi S, Decroly E, Bonnaud E, Hermant A, Guillemot JC, Debarnot C, Borg JP, Bouvet M, Canard B, Morelli X, Lécine P. Lugari A, et al. Among authors: morelli x. J Biol Chem. 2010 Oct 22;285(43):33230-33241. doi: 10.1074/jbc.M110.120014. Epub 2010 Aug 10. J Biol Chem. 2010. PMID: 20699222 Free PMC article.
85 results