Wiles MV - Search Results

1

Generation of improved humanized mouse models for human infectious diseases.

Brehm MA, Wiles MV, Greiner DL, Shultz LD. Brehm MA, et al. Among authors: wiles mv. J Immunol Methods. 2014 Aug;410:3-17. doi: 10.1016/j.jim.2014.02.011. Epub 2014 Mar 4. J Immunol Methods. 2014. PMID: 24607601 Free PMC article. Review.

2

Genetically engineered humanized mouse models for preclinical antibody studies.

Proetzel G, Wiles MV, Roopenian DC. Proetzel G, et al. Among authors: wiles mv. BioDrugs. 2014 Apr;28(2):171-80. doi: 10.1007/s40259-013-0071-0. BioDrugs. 2014. PMID: 24150980 Free PMC article. Review.

3

Albumin-deficient mouse models for studying metabolism of human albumin and pharmacokinetics of albumin-based drugs.

Roopenian DC, Low BE, Christianson GJ, Proetzel G, Sproule TJ, Wiles MV. Roopenian DC, et al. Among authors: wiles mv. MAbs. 2015;7(2):344-51. doi: 10.1080/19420862.2015.1008345. MAbs. 2015. PMID: 25654695 Free PMC article.

4

A Humanized Mouse Model to Study Human Albumin and Albumin Conjugates Pharmacokinetics.

Low BE, Wiles MV. Low BE, et al. Among authors: wiles mv. Methods Mol Biol. 2016;1438:115-22. doi: 10.1007/978-1-4939-3661-8_7. Methods Mol Biol. 2016. PMID: 27150087 Review.

5

Early induction of NRF2 antioxidant pathway by RHBDF2 mediates rapid cutaneous wound healing.

Hosur V, Burzenski LM, Stearns TM, Farley ML, Sundberg JP, Wiles MV, Shultz LD. Hosur V, et al. Among authors: wiles mv. Exp Mol Pathol. 2017 Apr;102(2):337-346. doi: 10.1016/j.yexmp.2017.03.003. Epub 2017 Mar 6. Exp Mol Pathol. 2017. PMID: 28268192 Free PMC article.

6

Development of Humanized Mice in the Age of Genome Editing.

Hosur V, Low BE, Avery C, Shultz LD, Wiles MV. Hosur V, et al. Among authors: wiles mv. J Cell Biochem. 2017 Oct;118(10):3043-3048. doi: 10.1002/jcb.26002. Epub 2017 May 15. J Cell Biochem. 2017. PMID: 28332231 Free PMC article.

7

Genetic deletion of amphiregulin restores the normal skin phenotype in a mouse model of the human skin disease tylosis.

Hosur V, Low BE, Shultz LD, Wiles MV. Hosur V, et al. Among authors: wiles mv. Biol Open. 2017 Aug 15;6(8):1174-1179. doi: 10.1242/bio.026260. Biol Open. 2017. PMID: 28655741 Free PMC article.

8

ADAM17 is essential for ectodomain shedding of the EGF-receptor ligand amphiregulin.

Hosur V, Farley ML, Burzenski LM, Shultz LD, Wiles MV. Hosur V, et al. Among authors: wiles mv. FEBS Open Bio. 2018 Mar 12;8(4):702-710. doi: 10.1002/2211-5463.12407. eCollection 2018 Apr. FEBS Open Bio. 2018. PMID: 29632822 Free PMC article.

9

RHBDF2-Regulated Growth Factor Signaling in a Rare Human Disease, Tylosis With Esophageal Cancer: What Can We Learn From Murine Models?

Hosur V, Farley ML, Low BE, Burzenski LM, Shultz LD, Wiles MV. Hosur V, et al. Among authors: wiles mv. Front Genet. 2018 Jul 4;9:233. doi: 10.3389/fgene.2018.00233. eCollection 2018. Front Genet. 2018. PMID: 30022999 Free PMC article.

10

Lack of acute xenogeneic graft- versus-host disease, but retention of T-cell function following engraftment of human peripheral blood mononuclear cells in NSG mice deficient in MHC class I and II expression.

Brehm MA, Kenney LL, Wiles MV, Low BE, Tisch RM, Burzenski L, Mueller C, Greiner DL, Shultz LD. Brehm MA, et al. Among authors: wiles mv. FASEB J. 2019 Mar;33(3):3137-3151. doi: 10.1096/fj.201800636R. Epub 2018 Nov 1. FASEB J. 2019. PMID: 30383447 Free PMC article.

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