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The transcriptional activities and cellular localization of the human estrogen receptor alpha are affected by the synonymous Ala87 mutation.
Fernández-Calero T, Astrada S, Alberti A, Horjales S, Arnal JF, Rovira C, Bollati-Fogolín M, Flouriot G, Marin M. Fernández-Calero T, et al. Among authors: arnal jf. J Steroid Biochem Mol Biol. 2014 Sep;143:99-104. doi: 10.1016/j.jsbmb.2014.02.016. Epub 2014 Mar 4. J Steroid Biochem Mol Biol. 2014. PMID: 24607813
The transactivating function 1 of estrogen receptor alpha is dispensable for the vasculoprotective actions of 17beta-estradiol.
Billon-Galés A, Fontaine C, Filipe C, Douin-Echinard V, Fouque MJ, Flouriot G, Gourdy P, Lenfant F, Laurell H, Krust A, Chambon P, Arnal JF. Billon-Galés A, et al. Among authors: arnal jf. Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):2053-8. doi: 10.1073/pnas.0808742106. Epub 2009 Feb 2. Proc Natl Acad Sci U S A. 2009. PMID: 19188600 Free PMC article.
Activation function 2 (AF2) of estrogen receptor-alpha is required for the atheroprotective action of estradiol but not to accelerate endothelial healing.
Billon-Galés A, Krust A, Fontaine C, Abot A, Flouriot G, Toutain C, Berges H, Gadeau AP, Lenfant F, Gourdy P, Chambon P, Arnal JF. Billon-Galés A, et al. Among authors: arnal jf. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13311-6. doi: 10.1073/pnas.1105632108. Epub 2011 Jul 25. Proc Natl Acad Sci U S A. 2011. PMID: 21788522 Free PMC article.
Mutation of the palmitoylation site of estrogen receptor α in vivo reveals tissue-specific roles for membrane versus nuclear actions.
Adlanmerini M, Solinhac R, Abot A, Fabre A, Raymond-Letron I, Guihot AL, Boudou F, Sautier L, Vessières E, Kim SH, Lière P, Fontaine C, Krust A, Chambon P, Katzenellenbogen JA, Gourdy P, Shaul PW, Henrion D, Arnal JF, Lenfant F. Adlanmerini M, et al. Among authors: arnal jf. Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):E283-90. doi: 10.1073/pnas.1322057111. Epub 2013 Dec 26. Proc Natl Acad Sci U S A. 2014. PMID: 24371309 Free PMC article.
228 results