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HBS1L-MYB intergenic variants modulate fetal hemoglobin via long-range MYB enhancers.
Stadhouders R, Aktuna S, Thongjuea S, Aghajanirefah A, Pourfarzad F, van Ijcken W, Lenhard B, Rooks H, Best S, Menzel S, Grosveld F, Thein SL, Soler E. Stadhouders R, et al. Among authors: menzel s. J Clin Invest. 2014 Apr;124(4):1699-710. doi: 10.1172/JCI71520. Epub 2014 Mar 10. J Clin Invest. 2014. PMID: 24614105 Free PMC article.
Intergenic variants of HBS1L-MYB are responsible for a major quantitative trait locus on chromosome 6q23 influencing fetal hemoglobin levels in adults.
Thein SL, Menzel S, Peng X, Best S, Jiang J, Close J, Silver N, Gerovasilli A, Ping C, Yamaguchi M, Wahlberg K, Ulug P, Spector TD, Garner C, Matsuda F, Farrall M, Lathrop M. Thein SL, et al. Among authors: menzel s. Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11346-51. doi: 10.1073/pnas.0611393104. Epub 2007 Jun 25. Proc Natl Acad Sci U S A. 2007. PMID: 17592125 Free PMC article.
Genetic architecture of hemoglobin F control.
Menzel S, Thein SL. Menzel S, et al. Curr Opin Hematol. 2009 May;16(3):179-186. doi: 10.1097/moh.0b013e328329d07a. Curr Opin Hematol. 2009. PMID: 19475730 Review. No abstract available.
284 results