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2'-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity.
Wu SY, Yang X, Gharpure KM, Hatakeyama H, Egli M, McGuire MH, Nagaraja AS, Miyake TM, Rupaimoole R, Pecot CV, Taylor M, Pradeep S, Sierant M, Rodriguez-Aguayo C, Choi HJ, Previs RA, Armaiz-Pena GN, Huang L, Martinez C, Hassell T, Ivan C, Sehgal V, Singhania R, Han HD, Su C, Kim JH, Dalton HJ, Kovvali C, Keyomarsi K, McMillan NA, Overwijk WW, Liu J, Lee JS, Baggerly KA, Lopez-Berestein G, Ram PT, Nawrot B, Sood AK. Wu SY, et al. Nat Commun. 2014 Mar 12;5:3459. doi: 10.1038/ncomms4459. Nat Commun. 2014. PMID: 24619206 Free PMC article.
Lipidic systems for in vivo siRNA delivery.
Wu SY, McMillan NA. Wu SY, et al. AAPS J. 2009 Dec;11(4):639-52. doi: 10.1208/s12248-009-9140-1. Epub 2009 Sep 9. AAPS J. 2009. PMID: 19757082 Free PMC article. Review.
New roles opined for OPCML.
Wu SY, Sood AK. Wu SY, et al. Cancer Discov. 2012 Feb;2(2):115-6. doi: 10.1158/2159-8290.CD-11-0356. Cancer Discov. 2012. PMID: 22585855 Free PMC article.
A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis.
Masiero M, Simões FC, Han HD, Snell C, Peterkin T, Bridges E, Mangala LS, Wu SY, Pradeep S, Li D, Han C, Dalton H, Lopez-Berestein G, Tuynman JB, Mortensen N, Li JL, Patient R, Sood AK, Banham AH, Harris AL, Buffa FM. Masiero M, et al. Among authors: wu sy. Cancer Cell. 2013 Aug 12;24(2):229-41. doi: 10.1016/j.ccr.2013.06.004. Epub 2013 Jul 18. Cancer Cell. 2013. PMID: 23871637 Free PMC article.
1,976 results