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Integrated next-generation sequencing and avatar mouse models for personalized cancer treatment.
Garralda E, Paz K, López-Casas PP, Jones S, Katz A, Kann LM, López-Rios F, Sarno F, Al-Shahrour F, Vasquez D, Bruckheimer E, Angiuoli SV, Calles A, Diaz LA, Velculescu VE, Valencia A, Sidransky D, Hidalgo M. Garralda E, et al. Among authors: valencia a. Clin Cancer Res. 2014 May 1;20(9):2476-84. doi: 10.1158/1078-0432.CCR-13-3047. Epub 2014 Mar 14. Clin Cancer Res. 2014. PMID: 24634382 Free PMC article.
From cancer genomes to cancer models: bridging the gaps.
Baudot A, Real FX, Izarzugaza JM, Valencia A. Baudot A, et al. Among authors: valencia a. EMBO Rep. 2009 Apr;10(4):359-66. doi: 10.1038/embor.2009.46. Epub 2009 Mar 20. EMBO Rep. 2009. PMID: 19305388 Free PMC article. Review.
Long-range epigenetic silencing associates with deregulation of Ikaros targets in colorectal cancer cells.
Javierre BM, Rodriguez-Ubreva J, Al-Shahrour F, Corominas M, Graña O, Ciudad L, Agirre X, Pisano DG, Valencia A, Roman-Gomez J, Calasanz MJ, Prosper F, Esteller M, Gonzalez-Sarmiento R, Ballestar E. Javierre BM, et al. Among authors: valencia a. Mol Cancer Res. 2011 Aug;9(8):1139-51. doi: 10.1158/1541-7786.MCR-10-0515. Epub 2011 Jul 7. Mol Cancer Res. 2011. PMID: 21737484
Transcriptional dissection of pancreatic tumors engrafted in mice.
Martinez-Garcia R, Juan D, Rausell A, Muñoz M, Baños N, Menéndez C, Lopez-Casas PP, Rico D, Valencia A, Hidalgo M. Martinez-Garcia R, et al. Among authors: valencia a. Genome Med. 2014 Apr 16;6(4):27. doi: 10.1186/gm544. eCollection 2014. Genome Med. 2014. PMID: 24739241 Free PMC article.
Precision medicine needs pioneering clinical bioinformaticians.
Gómez-López G, Dopazo J, Cigudosa JC, Valencia A, Al-Shahrour F. Gómez-López G, et al. Among authors: valencia a. Brief Bioinform. 2019 May 21;20(3):752-766. doi: 10.1093/bib/bbx144. Brief Bioinform. 2019. PMID: 29077790 Free article. Review.
PanDrugs: a novel method to prioritize anticancer drug treatments according to individual genomic data.
Piñeiro-Yáñez E, Reboiro-Jato M, Gómez-López G, Perales-Patón J, Troulé K, Rodríguez JM, Tejero H, Shimamura T, López-Casas PP, Carretero J, Valencia A, Hidalgo M, Glez-Peña D, Al-Shahrour F. Piñeiro-Yáñez E, et al. Among authors: valencia a. Genome Med. 2018 May 31;10(1):41. doi: 10.1186/s13073-018-0546-1. Genome Med. 2018. PMID: 29848362 Free PMC article.
vulcanSpot: a tool to prioritize therapeutic vulnerabilities in cancer.
Perales-Patón J, Di Domenico T, Fustero-Torre C, Piñeiro-Yáñez E, Carretero-Puche C, Tejero H, Valencia A, Gómez-López G, Al-Shahrour F. Perales-Patón J, et al. Among authors: valencia a. Bioinformatics. 2019 Nov 1;35(22):4846-4848. doi: 10.1093/bioinformatics/btz465. Bioinformatics. 2019. PMID: 31173067 Free PMC article.
955 results