Lysyl oxidase overexpression accelerates cardiac remodeling and aggravates angiotensin II-induced hypertrophy.
Galán M, Varona S, Guadall A, Orriols M, Navas M, Aguiló S, de Diego A, Navarro MA, García-Dorado D, Rodríguez-Sinovas A, Martínez-González J, Rodriguez C.
Galán M, et al. Among authors: navas m.
FASEB J. 2017 Sep;31(9):3787-3799. doi: 10.1096/fj.201601157RR. Epub 2017 May 18.
FASEB J. 2017.
PMID: 28522596
Our findings suggest that LOX induces an age-dependent disturbance of diastolic function and aggravates Ang II-induced hypertrophy, which provides novel insights into the role of LOX in cardiac performance.-Galan, M., Varona, S., Guadall, A., Orriols, M., Navas …
Our findings suggest that LOX induces an age-dependent disturbance of diastolic function and aggravates Ang II-induced hypertrophy, which pr …