Sachse FB - Search Results

1

Stoichiometry of altered hERG1 channel gating by small molecule activators.

Wu W, Sachse FB, Gardner A, Sanguinetti MC. Wu W, et al. Among authors: sachse fb. J Gen Physiol. 2014 Apr;143(4):499-512. doi: 10.1085/jgp.201311038. Epub 2014 Mar 17. J Gen Physiol. 2014. PMID: 24638994 Free PMC article.

2

Molecular determinants for activation of human ether-à-go-go-related gene 1 potassium channels by 3-nitro-n-(4-phenoxyphenyl) benzamide.

Garg V, Stary-Weinzinger A, Sachse F, Sanguinetti MC. Garg V, et al. Mol Pharmacol. 2011 Oct;80(4):630-7. doi: 10.1124/mol.111.073809. Epub 2011 Jul 8. Mol Pharmacol. 2011. PMID: 21743002 Free PMC article.

3

Cooperative interactions between R531 and acidic residues in the voltage sensing module of hERG1 channels.

Piper DR, Rupp J, Sachse FB, Sanguinetti MC, Tristani-Firouzi M. Piper DR, et al. Among authors: sachse fb. Cell Physiol Biochem. 2008;21(1-3):37-46. doi: 10.1159/000113745. Epub 2008 Jan 16. Cell Physiol Biochem. 2008. PMID: 18209470

4

Structural basis for ether-a-go-go-related gene K+ channel subtype-dependent activation by niflumic acid.

Fernandez D, Sargent J, Sachse FB, Sanguinetti MC. Fernandez D, et al. Among authors: sachse fb. Mol Pharmacol. 2008 Apr;73(4):1159-67. doi: 10.1124/mol.107.043505. Epub 2008 Jan 24. Mol Pharmacol. 2008. PMID: 18218980 Free PMC article.

5

PD-118057 contacts the pore helix of hERG1 channels to attenuate inactivation and enhance K+ conductance.

Perry M, Sachse FB, Abbruzzese J, Sanguinetti MC. Perry M, et al. Among authors: sachse fb. Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):20075-80. doi: 10.1073/pnas.0906597106. Epub 2009 Nov 5. Proc Natl Acad Sci U S A. 2009. PMID: 19892732 Free PMC article.

6

Modification of hERG1 channel gating by Cd2+.

Abbruzzese J, Sachse FB, Tristani-Firouzi M, Sanguinetti MC. Abbruzzese J, et al. Among authors: sachse fb. J Gen Physiol. 2010 Aug;136(2):203-24. doi: 10.1085/jgp.201010450. J Gen Physiol. 2010. PMID: 20660661 Free PMC article.

7

Tuning of EAG K(+) channel inactivation: molecular determinants of amplification by mutations and a small molecule.

Garg V, Sachse FB, Sanguinetti MC. Garg V, et al. Among authors: sachse fb. J Gen Physiol. 2012 Sep;140(3):307-24. doi: 10.1085/jgp.201210826. J Gen Physiol. 2012. PMID: 22930803 Free PMC article.

8

Ginsenoside Rg3, a Gating Modifier of EAG Family K+ Channels.

Wu W, Gardner A, Sachse FB, Sanguinetti MC. Wu W, et al. Among authors: sachse fb. Mol Pharmacol. 2016 Oct;90(4):469-82. doi: 10.1124/mol.116.104091. Epub 2016 Aug 8. Mol Pharmacol. 2016. PMID: 27502018 Free PMC article.

9

Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator.

Perry M, Sachse FB, Sanguinetti MC. Perry M, et al. Among authors: sachse fb. Proc Natl Acad Sci U S A. 2007 Aug 21;104(34):13827-32. doi: 10.1073/pnas.0703934104. Epub 2007 Aug 10. Proc Natl Acad Sci U S A. 2007. PMID: 17693551 Free PMC article.

10

Structural determinants of Kvbeta1.3-induced channel inactivation: a hairpin modulated by PIP2.

Decher N, Gonzalez T, Streit AK, Sachse FB, Renigunta V, Soom M, Heinemann SH, Daut J, Sanguinetti MC. Decher N, et al. Among authors: sachse fb. EMBO J. 2008 Dec 3;27(23):3164-74. doi: 10.1038/emboj.2008.231. Epub 2008 Nov 6. EMBO J. 2008. PMID: 18987637 Free PMC article.

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