Eggel A - Search Results

1

Accelerated dissociation of IgE-FcεRI complexes by disruptive inhibitors actively desensitizes allergic effector cells.

Eggel A, Baravalle G, Hobi G, Kim B, Buschor P, Forrer P, Shin JS, Vogel M, Stadler BM, Dahinden CA, Jardetzky TS. Eggel A, et al. J Allergy Clin Immunol. 2014 Jun;133(6):1709-19.e8. doi: 10.1016/j.jaci.2014.02.005. Epub 2014 Mar 15. J Allergy Clin Immunol. 2014. PMID: 24642143 Free PMC article.

2

DARPins as bispecific receptor antagonists analyzed for immunoglobulin E receptor blockage.

Eggel A, Baumann MJ, Amstutz P, Stadler BM, Vogel M. Eggel A, et al. J Mol Biol. 2009 Oct 30;393(3):598-607. doi: 10.1016/j.jmb.2009.08.014. Epub 2009 Aug 13. J Mol Biol. 2009. PMID: 19683003

3

DARPins against a functional IgE epitope.

Baumann MJ, Eggel A, Amstutz P, Stadler BM, Vogel M. Baumann MJ, et al. Among authors: eggel a. Immunol Lett. 2010 Oct 30;133(2):78-84. doi: 10.1016/j.imlet.2010.07.005. Epub 2010 Jul 29. Immunol Lett. 2010. PMID: 20673836

4

Inhibition of ongoing allergic reactions using a novel anti-IgE DARPin-Fc fusion protein.

Eggel A, Buschor P, Baumann MJ, Amstutz P, Stadler BM, Vogel M. Eggel A, et al. Allergy. 2011 Jul;66(7):961-8. doi: 10.1111/j.1398-9995.2011.02546.x. Epub 2011 Jan 28. Allergy. 2011. PMID: 21272035

5

An engineered disulfide bond reversibly traps the IgE-Fc3-4 in a closed, nonreceptor binding conformation.

Wurzburg BA, Kim B, Tarchevskaya SS, Eggel A, Vogel M, Jardetzky TS. Wurzburg BA, et al. Among authors: eggel a. J Biol Chem. 2012 Oct 19;287(43):36251-7. doi: 10.1074/jbc.M112.407502. Epub 2012 Sep 4. J Biol Chem. 2012. PMID: 22948141 Free PMC article.

6

A time-resolved fluorescence resonance energy transfer assay suitable for high-throughput screening for inhibitors of immunoglobulin E-receptor interactions.

Kim B, Tarchevskaya SS, Eggel A, Vogel M, Jardetzky TS. Kim B, et al. Among authors: eggel a. Anal Biochem. 2012 Dec 15;431(2):84-9. doi: 10.1016/j.ab.2012.09.010. Epub 2012 Sep 18. Anal Biochem. 2012. PMID: 22995065 Free PMC article.

7

Accelerated disassembly of IgE-receptor complexes by a disruptive macromolecular inhibitor.

Kim B, Eggel A, Tarchevskaya SS, Vogel M, Prinz H, Jardetzky TS. Kim B, et al. Among authors: eggel a. Nature. 2012 Nov 22;491(7425):613-7. doi: 10.1038/nature11546. Epub 2012 Oct 28. Nature. 2012. PMID: 23103871 Free PMC article.

8

Improved FcγRIIb targeting functionally translates into enhanced inhibition of basophil activation.

Buschor P, Eggel A, Zellweger F, Stadler BM, Vogel M. Buschor P, et al. Among authors: eggel a. Int Arch Allergy Immunol. 2014;163(3):206-14. doi: 10.1159/000358487. Epub 2014 Feb 14. Int Arch Allergy Immunol. 2014. PMID: 24557487

9

Structural basis of omalizumab therapy and omalizumab-mediated IgE exchange.

Pennington LF, Tarchevskaya S, Brigger D, Sathiyamoorthy K, Graham MT, Nadeau KC, Eggel A, Jardetzky TS. Pennington LF, et al. Among authors: eggel a. Nat Commun. 2016 May 19;7:11610. doi: 10.1038/ncomms11610. Nat Commun. 2016. PMID: 27194387 Free PMC article.

10

IgE-associated allergic disorders: recent advances in etiology, diagnosis, and treatment.

Zellweger F, Eggel A. Zellweger F, et al. Among authors: eggel a. Allergy. 2016 Dec;71(12):1652-1661. doi: 10.1111/all.13059. Allergy. 2016. PMID: 27709638 Review.

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