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New pyrazolobenzothiazine derivatives as hepatitis C virus NS5B polymerase palm site I inhibitors.
Manfroni G, Manvar D, Barreca ML, Kaushik-Basu N, Leyssen P, Paeshuyse J, Cannalire R, Iraci N, Basu A, Chudaev M, Zamperini C, Dreassi E, Sabatini S, Tabarrini O, Neyts J, Cecchetti V. Manfroni G, et al. Among authors: paeshuyse j. J Med Chem. 2014 Apr 24;57(8):3247-62. doi: 10.1021/jm401688h. Epub 2014 Apr 2. J Med Chem. 2014. PMID: 24654886 Free PMC article.
The versatile nature of the 6-aminoquinolone scaffold: identification of submicromolar hepatitis C virus NS5B inhibitors.
Manfroni G, Cannalire R, Barreca ML, Kaushik-Basu N, Leyssen P, Winquist J, Iraci N, Manvar D, Paeshuyse J, Guhamazumder R, Basu A, Sabatini S, Tabarrini O, Danielson UH, Neyts J, Cecchetti V. Manfroni G, et al. Among authors: paeshuyse j. J Med Chem. 2014 Mar 13;57(5):1952-63. doi: 10.1021/jm401362f. Epub 2013 Nov 6. J Med Chem. 2014. PMID: 24131104 Free PMC article.
Linear and branched alkyl-esters and amides of gallic acid and other (mono-, di- and tri-) hydroxy benzoyl derivatives as promising anti-HCV inhibitors.
Rivero-Buceta E, Carrero P, Doyagüez EG, Madrona A, Quesada E, Camarasa MJ, Peréz-Pérez MJ, Leyssen P, Paeshuyse J, Balzarini J, Neyts J, San-Félix A. Rivero-Buceta E, et al. Among authors: paeshuyse j. Eur J Med Chem. 2015 Mar 6;92:656-71. doi: 10.1016/j.ejmech.2015.01.033. Epub 2015 Jan 17. Eur J Med Chem. 2015. PMID: 25617695 Free article.
Comparative in vitro anti-hepatitis C virus activities of a selected series of polymerase, protease, and helicase inhibitors.
Paeshuyse J, Vliegen I, Coelmont L, Leyssen P, Tabarrini O, Herdewijn P, Mittendorfer H, Easmon J, Cecchetti V, Bartenschlager R, Puerstinger G, Neyts J. Paeshuyse J, et al. Antimicrob Agents Chemother. 2008 Sep;52(9):3433-7. doi: 10.1128/AAC.01534-07. Epub 2008 Jul 14. Antimicrob Agents Chemother. 2008. PMID: 18625766 Free PMC article.
78 results