Hromas R - Search Results

1

Fidelity of end joining in mammalian episomes and the impact of Metnase on joint processing.

Rath A, Hromas R, De Benedetti A. Rath A, et al. Among authors: hromas r. BMC Mol Biol. 2014 Mar 22;15:6. doi: 10.1186/1471-2199-15-6. BMC Mol Biol. 2014. PMID: 24655462 Free PMC article.

2

The SET domain protein Metnase mediates foreign DNA integration and links integration to nonhomologous end-joining repair.

Lee SH, Oshige M, Durant ST, Rasila KK, Williamson EA, Ramsey H, Kwan L, Nickoloff JA, Hromas R. Lee SH, et al. Among authors: hromas r. Proc Natl Acad Sci U S A. 2005 Dec 13;102(50):18075-80. doi: 10.1073/pnas.0503676102. Epub 2005 Dec 6. Proc Natl Acad Sci U S A. 2005. PMID: 16332963 Free PMC article.

3

Biochemical characterization of metnase's endonuclease activity and its role in NHEJ repair.

Beck BD, Lee SS, Williamson E, Hromas RA, Lee SH. Beck BD, et al. Biochemistry. 2011 May 24;50(20):4360-70. doi: 10.1021/bi200333k. Epub 2011 Apr 27. Biochemistry. 2011. PMID: 21491884 Free PMC article.

4

The DDN catalytic motif is required for Metnase functions in non-homologous end joining (NHEJ) repair and replication restart.

Kim HS, Chen Q, Kim SK, Nickoloff JA, Hromas R, Georgiadis MM, Lee SH. Kim HS, et al. Among authors: hromas r. J Biol Chem. 2014 Apr 11;289(15):10930-10938. doi: 10.1074/jbc.M113.533216. Epub 2014 Feb 25. J Biol Chem. 2014. PMID: 24573677 Free PMC article.

5

Regulation of Metnase's TIR binding activity by its binding partner, Pso4.

Beck BD, Lee SS, Hromas R, Lee SH. Beck BD, et al. Among authors: hromas r. Arch Biochem Biophys. 2010 Jun 15;498(2):89-94. doi: 10.1016/j.abb.2010.04.011. Epub 2010 Apr 20. Arch Biochem Biophys. 2010. PMID: 20416268 Free PMC article.

6

Metnase Mediates Loading of Exonuclease 1 onto Single Strand Overhang DNA for End Resection at Stalled Replication Forks.

Kim HS, Williamson EA, Nickoloff JA, Hromas RA, Lee SH. Kim HS, et al. J Biol Chem. 2017 Jan 27;292(4):1414-1425. doi: 10.1074/jbc.M116.745646. Epub 2016 Dec 14. J Biol Chem. 2017. PMID: 27974460 Free PMC article.

7

The SET Domain Is Essential for Metnase Functions in Replication Restart and the 5' End of SS-Overhang Cleavage.

Kim HS, Kim SK, Hromas R, Lee SH. Kim HS, et al. Among authors: hromas r. PLoS One. 2015 Oct 5;10(10):e0139418. doi: 10.1371/journal.pone.0139418. eCollection 2015. PLoS One. 2015. PMID: 26437079 Free PMC article.

8

More forks on the road to replication stress recovery.

Allen C, Ashley AK, Hromas R, Nickoloff JA. Allen C, et al. Among authors: hromas r. J Mol Cell Biol. 2011 Feb;3(1):4-12. doi: 10.1093/jmcb/mjq049. J Mol Cell Biol. 2011. PMID: 21278446 Free PMC article. Review.

9

Human Pso4 is a metnase (SETMAR)-binding partner that regulates metnase function in DNA repair.

Beck BD, Park SJ, Lee YJ, Roman Y, Hromas RA, Lee SH. Beck BD, et al. J Biol Chem. 2008 Apr 4;283(14):9023-30. doi: 10.1074/jbc.M800150200. Epub 2008 Feb 8. J Biol Chem. 2008. PMID: 18263876 Free PMC article.

10

Biochemical characterization of a SET and transposase fusion protein, Metnase: its DNA binding and DNA cleavage activity.

Roman Y, Oshige M, Lee YJ, Goodwin K, Georgiadis MM, Hromas RA, Lee SH. Roman Y, et al. Biochemistry. 2007 Oct 9;46(40):11369-76. doi: 10.1021/bi7005477. Epub 2007 Sep 18. Biochemistry. 2007. PMID: 17877369 Free PMC article.

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