O'Reilly NJ - Search Results

1

Phosphorylation-dependent PIH1D1 interactions define substrate specificity of the R2TP cochaperone complex.

Hořejší Z, Stach L, Flower TG, Joshi D, Flynn H, Skehel JM, O'Reilly NJ, Ogrodowicz RW, Smerdon SJ, Boulton SJ. Hořejší Z, et al. Cell Rep. 2014 Apr 10;7(1):19-26. doi: 10.1016/j.celrep.2014.03.013. Epub 2014 Mar 20. Cell Rep. 2014. PMID: 24656813 Free PMC article.

2

Distinct binding modes of two epitopes in Gab2 that interact with the SH3C domain of Grb2.

Harkiolaki M, Tsirka T, Lewitzky M, Simister PC, Joshi D, Bird LE, Jones EY, O'Reilly N, Feller SM. Harkiolaki M, et al. Structure. 2009 Jun 10;17(6):809-22. doi: 10.1016/j.str.2009.03.017. Structure. 2009. PMID: 19523899 Free article.

3

14-3-3 proteins interact with a hybrid prenyl-phosphorylation motif to inhibit G proteins.

Riou P, Kjær S, Garg R, Purkiss A, George R, Cain RJ, Bineva G, Reymond N, McColl B, Thompson AJ, O'Reilly N, McDonald NQ, Parker PJ, Ridley AJ. Riou P, et al. Cell. 2013 Apr 25;153(3):640-53. doi: 10.1016/j.cell.2013.03.044. Cell. 2013. PMID: 23622247 Free PMC article.

4

Differential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3 (RIN3).

Rouka E, Simister PC, Janning M, Kumbrink J, Konstantinou T, Muniz JR, Joshi D, O'Reilly N, Volkmer R, Ritter B, Knapp S, von Delft F, Kirsch KH, Feller SM. Rouka E, et al. J Biol Chem. 2015 Oct 16;290(42):25275-92. doi: 10.1074/jbc.M115.637207. Epub 2015 Aug 20. J Biol Chem. 2015. PMID: 26296892 Free PMC article.

5

aPKC Inhibition by Par3 CR3 Flanking Regions Controls Substrate Access and Underpins Apical-Junctional Polarization.

Soriano EV, Ivanova ME, Fletcher G, Riou P, Knowles PP, Barnouin K, Purkiss A, Kostelecky B, Saiu P, Linch M, Elbediwy A, Kjær S, O'Reilly N, Snijders AP, Parker PJ, Thompson BJ, McDonald NQ. Soriano EV, et al. Dev Cell. 2016 Aug 22;38(4):384-98. doi: 10.1016/j.devcel.2016.07.018. Dev Cell. 2016. PMID: 27554858 Free PMC article.

6

MRE11 stability is regulated by CK2-dependent interaction with R2TP complex.

von Morgen P, Burdova K, Flower TG, O'Reilly NJ, Boulton SJ, Smerdon SJ, Macurek L, Hořejší Z. von Morgen P, et al. Oncogene. 2017 Aug 24;36(34):4943-4950. doi: 10.1038/onc.2017.99. Epub 2017 Apr 24. Oncogene. 2017. PMID: 28436950 Free PMC article.

7

A Meiotic Checkpoint Alters Repair Partner Bias to Permit Inter-sister Repair of Persistent DSBs.

Garcia-Muse T, Galindo-Diaz U, Garcia-Rubio M, Martin JS, Polanowska J, O'Reilly N, Aguilera A, Boulton SJ. Garcia-Muse T, et al. Cell Rep. 2019 Jan 15;26(3):775-787.e5. doi: 10.1016/j.celrep.2018.12.074. Cell Rep. 2019. PMID: 30650366 Free PMC article.

8

Molecular determinants regulating selective binding of autophagy adapters and receptors to ATG8 proteins.

Wirth M, Zhang W, Razi M, Nyoni L, Joshi D, O'Reilly N, Johansen T, Tooze SA, Mouilleron S. Wirth M, et al. Nat Commun. 2019 May 3;10(1):2055. doi: 10.1038/s41467-019-10059-6. Nat Commun. 2019. PMID: 31053714 Free PMC article.

9

Glypicans shield the Wnt lipid moiety to enable signalling at a distance.

McGough IJ, Vecchia L, Bishop B, Malinauskas T, Beckett K, Joshi D, O'Reilly N, Siebold C, Jones EY, Vincent JP. McGough IJ, et al. Nature. 2020 Sep;585(7823):85-90. doi: 10.1038/s41586-020-2498-z. Epub 2020 Jul 22. Nature. 2020. PMID: 32699409 Free PMC article.

10

A Structure-Based Mechanism for DNA Entry into the Cohesin Ring.

Higashi TL, Eickhoff P, Sousa JS, Locke J, Nans A, Flynn HR, Snijders AP, Papageorgiou G, O'Reilly N, Chen ZA, O'Reilly FJ, Rappsilber J, Costa A, Uhlmann F. Higashi TL, et al. Mol Cell. 2020 Sep 17;79(6):917-933.e9. doi: 10.1016/j.molcel.2020.07.013. Epub 2020 Aug 4. Mol Cell. 2020. PMID: 32755595 Free PMC article.

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