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An activin receptor IIA ligand trap corrects ineffective erythropoiesis in β-thalassemia.
Dussiot M, Maciel TT, Fricot A, Chartier C, Negre O, Veiga J, Grapton D, Paubelle E, Payen E, Beuzard Y, Leboulch P, Ribeil JA, Arlet JB, Coté F, Courtois G, Ginzburg YZ, Daniel TO, Chopra R, Sung V, Hermine O, Moura IC. Dussiot M, et al. Among authors: arlet jb. Nat Med. 2014 Apr;20(4):398-407. doi: 10.1038/nm.3468. Epub 2014 Mar 23. Nat Med. 2014. PMID: 24658077 Free PMC article.
Ineffective erythropoiesis in β -thalassemia.
Ribeil JA, Arlet JB, Dussiot M, Moura IC, Courtois G, Hermine O. Ribeil JA, et al. Among authors: arlet jb. ScientificWorldJournal. 2013 Mar 28;2013:394295. doi: 10.1155/2013/394295. Print 2013. ScientificWorldJournal. 2013. PMID: 23606813 Free PMC article. Review.
HSP70 sequestration by free α-globin promotes ineffective erythropoiesis in β-thalassaemia.
Arlet JB, Ribeil JA, Guillem F, Negre O, Hazoume A, Marcion G, Beuzard Y, Dussiot M, Moura IC, Demarest S, de Beauchêne IC, Belaid-Choucair Z, Sevin M, Maciel TT, Auclair C, Leboulch P, Chretien S, Tchertanov L, Baudin-Creuza V, Seigneuric R, Fontenay M, Garrido C, Hermine O, Courtois G. Arlet JB, et al. Nature. 2014 Oct 9;514(7521):242-6. doi: 10.1038/nature13614. Epub 2014 Aug 24. Nature. 2014. PMID: 25156257
[HSP70 regulates ineffective erythropoiesis in beta-thalassaemia].
Arlet JB, Ribeil JA, Guillem F, Hermine O, Courtois G. Arlet JB, et al. Med Sci (Paris). 2015 Jan;31(1):9-11. doi: 10.1051/medsci/20153101002. Epub 2015 Feb 6. Med Sci (Paris). 2015. PMID: 25658720 Free article. French. No abstract available.
XPO1 regulates erythroid differentiation and is a new target for the treatment of β-thalassemia.
Guillem F, Dussiot M, Colin E, Suriyun T, Arlet JB, Goudin N, Marcion G, Seigneuric R, Causse S, Gonin P, Gastou M, Deloger M, Rossignol J, Lamarque M, Choucair ZB, Gautier EF, Ducamp S, Vandekerckhove J, Moura IC, Maciel TT, Garrido C, An X, Mayeux P, Mohandas N, Courtois G, Hermine O. Guillem F, et al. Among authors: arlet jb. Haematologica. 2020 Sep 1;105(9):2240-2249. doi: 10.3324/haematol.2018.210054. Haematologica. 2020. PMID: 33054049 Free PMC article.
Protein-based therapeutic for anemia caused by dyserythropoiesis.
Arlet JB, Guillem F, Lamarque M, Dussiot M, Maciel T, Moura I, Hermine O, Courtois G. Arlet JB, et al. Expert Rev Proteomics. 2016 Nov;13(11):983-992. doi: 10.1080/14789450.2016.1240622. Epub 2016 Oct 6. Expert Rev Proteomics. 2016. PMID: 27661264
Sotatercept, a novel transforming growth factor β ligand trap, improves anemia in β-thalassemia: a phase II, open-label, dose-finding study.
Cappellini MD, Porter J, Origa R, Forni GL, Voskaridou E, Galactéros F, Taher AT, Arlet JB, Ribeil JA, Garbowski M, Graziadei G, Brouzes C, Semeraro M, Laadem A, Miteva D, Zou J, Sung V, Zinger T, Attie KM, Hermine O. Cappellini MD, et al. Among authors: arlet jb. Haematologica. 2019 Mar;104(3):477-484. doi: 10.3324/haematol.2018.198887. Epub 2018 Oct 18. Haematologica. 2019. PMID: 30337358 Free PMC article. Clinical Trial.
Unexpected macrophage-independent dyserythropoiesis in Gaucher disease.
Reihani N, Arlet JB, Dussiot M, de Villemeur TB, Belmatoug N, Rose C, Colin-Aronovicz Y, Hermine O, Le Van Kim C, Franco M. Reihani N, et al. Among authors: arlet jb. Haematologica. 2016 Dec;101(12):1489-1498. doi: 10.3324/haematol.2016.147546. Epub 2016 Jul 28. Haematologica. 2016. PMID: 27470603 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 31753924
399 results